Could fiber be the key to better gut health for short bowel patients?
NCT ID NCT07186608
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed study looked at whether specific dietary fibers can improve nutrition and gut barrier function in people with short bowel syndrome. Ten adults with type II or III short bowel syndrome took dietary fiber, and researchers measured changes in blood and stool samples. The goal was to see if fiber helps the remaining intestine adapt and work better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dietary fiber
- What this could lead to
- If it works, this could point toward a simple dietary supplement to help people with short bowel syndrome absorb nutrients better and reduce dependence on IV nutrition.
- What could go wrong
- This was a very small study with only 10 people, no control group, and it is already completed. Results may not apply to everyone, and the benefits might be modest or not reproducible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
10 people
The number who actually took part.
- Started
-
Feb 2025
- Finished
-
Aug 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
All participants in Cohort 1 were recruited at the Eastern Theatre Command General Hospital (Nanjing, China) and provided written informed consent. The primary inclusion criterion was a confirmed diagnosis of type II or type III short bowel syndrome in patients aged 18 -70 years. Participants were excluded if they had other gastrointestinal diseases, malignant tumours, autoimmune diseases, infectious diseases or renal insufficiency (severe kidney disease with creatinine levels exceeding 3.0 mg/dL), or if they had taken antibiotics for more than three days within the preceding three months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Eastern Theater Command General Hospital
Nanjing, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Measuring hidden energy needs: a clue to better nutrition for gut failure patients
- Weekly shot could help people with short bowel syndrome absorb more fluids
- New drug could cut IV nutrition needs for short bowel patients
- Could a Plant-Based powder cut the need for IV nutrition?
- Growth hormone shows promise for weaning kids off IV nutrition