SEZARY SYNDROME
Clinical trials for SEZARY SYNDROME explained in plain language.
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First-in-Human trial tests 'Supercharged' immune cells to hunt lymphoma
Disease control OngoingThis is a first-in-human study to test the safety of a new type of engineered immune cell therapy for adults with specific lymphomas that have returned or not responded to prior treatments. Researchers modify a patient's own T-cells to better recognize and attack cancer cells car…
Matched conditions: SEZARY SYNDROME
Phase: PHASE1 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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New combo therapy tested for Tough-to-Treat skin cancer
Disease control OngoingThis study is testing whether combining two existing drugs, pembrolizumab and gemcitabine, can help control advanced forms of a rare skin cancer called mycosis fungoides or Sézary syndrome. It is for adults whose disease has worsened after at least one prior treatment. The main g…
Matched conditions: SEZARY SYNDROME
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Virus + drug combo tested for Tough-to-Treat skin cancers
Disease control OngoingThis study is testing a two-part treatment for patients with advanced skin cancers or rare lymphomas that have not responded to other therapies. First, a modified virus is injected directly into tumors to help the immune system recognize cancer. Then, an immunotherapy drug is giv…
Matched conditions: SEZARY SYNDROME
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 24, 2026 12:03 UTC
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New drug tested for Tough-to-Treat skin cancer
Disease control OngoingThis early-stage study is testing a new drug called tulmimetostat (DZR123) in patients with advanced mycosis fungoides or Sézary syndrome, which are types of skin lymphoma. The main goal is to check if the drug is safe and to find the right dose for future studies. Researchers wi…
Matched conditions: SEZARY SYNDROME
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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New hope for patients with aggressive lymphoma that Won't respond
Disease control OngoingThis study is testing two drugs, durvalumab and lenalidomide, to see if they can help control advanced T-cell lymphomas that have come back or stopped responding to other treatments. It aims to find the safest dose and see how well the drugs work, either alone or together, for pa…
Matched conditions: SEZARY SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 11, 2026 14:53 UTC