SEVERE ASTHMA

This study looks at whether people with severe asthma who are taking the drug tezepelumab can safely cut back on their other asthma medicines without losing control of their symptoms. About 400 participants aged 12 to 80 will try to reduce or stop certain controller medications o…

This study tests a new medicine called GB-0895 for people with severe asthma that is not controlled by standard inhalers. About 786 adults and teens aged 12 to 80 will get either GB-0895 or a placebo injection every 6 months for a year. The goal is to see if GB-0895 reduces the n…

This study tests a procedure called bronchial thermoplasty (BT) for people with severe asthma who still have flare-ups despite using the best available medicines, including biologics. BT uses a thin tube to deliver heat to the airway walls, aiming to reduce asthma attacks and imp…

This study tests whether benralizumab can help people with severe asthma and a lung condition called allergic bronchopulmonary aspergillosis (ABPA). The goal is to reduce the number of asthma attacks that need steroids and improve quality of life. The study will enroll 20 adults …

This study tests a new medicine called GB-0895 for people aged 12 to 80 with severe asthma that is not controlled by standard inhalers. Participants will receive either GB-0895 or a placebo every 6 months for a year. The goal is to see if GB-0895 can reduce the number of serious …

This study tests an experimental drug called FB704A in adults with severe asthma. The goal is to see if it is safe and can help control asthma symptoms. About 20 participants will receive either the drug or a placebo over 8 weeks, with follow-up for 12 more weeks.

This observational study aims to find out how many adults with severe asthma in Thailand achieve remission and what factors might help. Researchers will collect data from 230 participants through questionnaires, lung function tests, and a blood test. The study does not provide tr…

This study is creating a large database and biobank from 2200 people with chronic inflammatory diseases like lupus, multiple sclerosis, and severe asthma. Researchers will track disease activity, quality of life, and treatment responses over time. The goal is to find new markers …

This study looks at how mucus plugs block airways in people with severe asthma. Using special MRI scans, researchers will measure how these plugs affect air flow and gas exchange in the lungs. The goal is to better understand the problem, not to test a new treatment. About 5 adul…

This study is a registry that collects health information from 714 Canadian adults with severe asthma over five years. Researchers will track treatments, symptoms, and asthma attacks to learn what works best. The goal is to use this real-world data to improve care for people with…

This study is a registry that will collect information from 5,000 people with severe asthma who are treated at specialized clinics. The goal is to track their health over time, see how well they follow their treatment plans, and understand which patients might benefit from newer …

This study looks at how mucus plugs in the lungs of people with severe asthma affect their breathing. Researchers will use special MRI scans to see which parts of the lung are blocked. They will also check if a new medicine (biologic therapy) helps improve airflow after 4 and 12 …

This study will look at 5,000 adults in Russia who have severe asthma that is not well controlled. Researchers will collect information on the medicines patients are already taking and their health details. The goal is to better understand current treatment patterns and patient c…