Canadian severe asthma registry aims to unlock better treatments
NCT ID NCT04045587
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is a registry that collects health information from 714 Canadian adults with severe asthma over five years. Researchers will track symptoms, medication use, and lung function to better understand the disease and how patients respond to current treatments. No new drugs or therapies are being tested.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this registry could help doctors better understand severe asthma and improve treatment guidelines for patients.
- What could go wrong
- This is an observational study, not a clinical trial of a new treatment. It collects data only and does not test any intervention, so direct patient benefits are not guaranteed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 714 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2018
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will be selected from respirology/pulmonary clinics across Canada. Participants will be identified and recruited by the study investigators and study staff based on their clinical presentation.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants 18 years or older * Participants receiving treatment according to GINA Step 5 or uncontrolled in GINA Step 4 (uncontrolled is defined as having severe asthma symptoms or frequent exacerbations) Exclusion Criteria: -Participants with mild to moderate asthma
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
11 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Inspiration Research Limited
RECRUITINGToronto, Ontario, M5T3A9, Canada
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Kingston General Hospital
RECRUITINGKingston, Ontario, Canada
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McGill University
NOT_YET_RECRUITINGMontreal, Quebec, H4A3J1, Canada
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Synergy MD Specialty Group
RECRUITINGEdmonton, Alberta, Canada
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The Ottawa Hospital
RECRUITINGOttawa, Ontario, Canada
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University of Alberta
RECRUITINGEdmonton, Alberta, T6G2G3, Canada
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University of British Columbia
RECRUITINGVancouver, British Columbia, V5Z1M9, Canada
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University of British Columbia
RECRUITINGVancouver, British Columbia, V6Z1Y6, Canada
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University of Saskatchewan
ACTIVE_NOT_RECRUITINGSaskatoon, Saskatchewan, Canada
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University of Western Ontario
NOT_YET_RECRUITINGLondon, Ontario, Canada
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Université Laval
RECRUITINGQuebéc City, Quebéc, G1V4G5, Canada
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Université de Sherbrooke
RECRUITINGSherbrooke, Quebec, Canada
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