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Canadian severe asthma registry aims to unlock better treatments

NCT ID NCT04045587

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is a registry that collects health information from 714 Canadian adults with severe asthma over five years. Researchers will track symptoms, medication use, and lung function to better understand the disease and how patients respond to current treatments. No new drugs or therapies are being tested.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this registry could help doctors better understand severe asthma and improve treatment guidelines for patients.
What could go wrong
This is an observational study, not a clinical trial of a new treatment. It collects data only and does not test any intervention, so direct patient benefits are not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 714 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2018

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will be selected from respirology/pulmonary clinics across Canada. Participants will be identified and recruited by the study investigators and study staff based on their clinical presentation.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants 18 years or older * Participants receiving treatment according to GINA Step 5 or uncontrolled in GINA Step 4 (uncontrolled is defined as having severe asthma symptoms or frequent exacerbations) Exclusion Criteria: -Participants with mild to moderate asthma

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    11 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Inspiration Research Limited

    RECRUITING

    Toronto, Ontario, M5T3A9, Canada

  • Kingston General Hospital

    RECRUITING

    Kingston, Ontario, Canada

  • McGill University

    NOT_YET_RECRUITING

    Montreal, Quebec, H4A3J1, Canada

  • Synergy MD Specialty Group

    RECRUITING

    Edmonton, Alberta, Canada

  • The Ottawa Hospital

    RECRUITING

    Ottawa, Ontario, Canada

  • University of Alberta

    RECRUITING

    Edmonton, Alberta, T6G2G3, Canada

  • University of British Columbia

    RECRUITING

    Vancouver, British Columbia, V5Z1M9, Canada

  • University of British Columbia

    RECRUITING

    Vancouver, British Columbia, V6Z1Y6, Canada

  • University of Saskatchewan

    ACTIVE_NOT_RECRUITING

    Saskatoon, Saskatchewan, Canada

  • University of Western Ontario

    NOT_YET_RECRUITING

    London, Ontario, Canada

  • Université Laval

    RECRUITING

    Quebéc City, Quebéc, G1V4G5, Canada

  • Université de Sherbrooke

    RECRUITING

    Sherbrooke, Quebec, Canada

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