SEVERE AORTIC STENOSIS
Clinical trials for SEVERE AORTIC STENOSIS explained in plain language.
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New heart valve study aims to improve safety for severe aortic stenosis patients in japan
Disease control Recruiting nowThis study looks at how safe and effective the Navitor heart valve is for people with severe aortic stenosis in everyday medical practice in Japan. About 100 participants will get the valve and be followed for 30 days to check survival and any leakage around the valve. The goal i…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 26, 2026 06:11 UTC
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New biomimetic heart valve faces off against standard TAVR in major trial
Disease control Recruiting nowThis study compares a new heart valve, the DurAVR®, to standard TAVR valves in people with severe aortic stenosis (a narrowed heart valve). About 1650 participants will be randomly assigned to get either the new valve or a standard one and will be followed for up to 10 years. The…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Anteris Technologies Ltd. • Aim: Disease control
Last updated May 26, 2026 06:03 UTC
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Heart-Lung machine before valve surgery may save lives in High-Risk patients
Disease control Recruiting nowThis study tests whether using a heart-lung machine (ECMO) before a complex valve replacement can prevent death, cardiac arrest, or emergency surgery in high-risk patients with severe aortic stenosis. About 30 adults who are unstable or have tricky heart anatomy will receive this…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: Atlantic Health System • Aim: Disease control
Last updated May 26, 2026 05:51 UTC
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Could skipping a Pre-Surgery test make heart valve replacement safer?
Disease control Recruiting nowThis study looks at whether people with severe aortic stenosis can safely skip a routine heart artery check (coronary angiogram) before their valve replacement procedure (TAVI). About 620 participants who do not have chest pain will be randomly assigned to either the standard pat…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Rede Optimus Hospitalar SA • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Heart valve study: which blood thinner works best after TAVR?
Disease control Recruiting nowThis study looks at two common blood thinners, aspirin and clopidogrel, to see which one better prevents small blood clots on the new heart valve after a TAVR procedure. About 254 people with severe aortic stenosis will take both drugs for 4 weeks after surgery, then switch to ju…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Yonsei University • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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New heart valve trial aims to improve survival in severe aortic stenosis
Disease control Recruiting nowThis study is testing the safety and effectiveness of the RENATUS transcatheter aortic valve system in 800 people with severe aortic stenosis (a narrowed heart valve). Participants receive the valve through a less invasive procedure. The main goal is to see how many people surviv…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Beijing Balance Medical Technology Co., Ltd • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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One stitch or two? new trial aims to simplify heart valve procedure
Disease control Recruiting nowThis study looks at whether using one closure device instead of two is just as safe for closing the blood vessel after a minimally invasive heart valve replacement (TAVR). About 876 people with severe aortic stenosis will take part. The goal is to see if using a single device can…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Can a smarter CT scan improve heart surgery decisions?
Knowledge-focused Recruiting nowThis study looks at whether adding a special CT scan (CT-FFR) to the usual heart CT can help doctors decide the best way to treat blocked arteries in people with severe aortic stenosis. About 300 people scheduled for valve replacement will be split into two groups: one where trea…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Yan'an Affiliated Hospital of Kunming Medical University • Aim: Knowledge-focused
Last updated May 26, 2026 04:38 UTC