Severe aortic stenosis
Clinical trials for Severe aortic stenosis explained in plain language.
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Heart valve trial asks: do we really need that extra artery test?
Disease control By invitation onlyThis study looks at people with severe aortic stenosis who need a new heart valve (TAVI). Normally, doctors do a coronary angiogram first to check for blocked arteries. But this test can cause kidney damage or bleeding, especially in older patients. The trial will compare the usu…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: Rede Optimus Hospitalar SA • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Less invasive heart valve replacement matches surgery in large trial
Disease control OngoingThis large study compared two treatments for severe aortic stenosis (a narrowed heart valve) in 1,746 patients at intermediate risk for surgery. One group got a less invasive procedure called TAVI (a new valve inserted through a tube in the artery), and the other had open-heart s…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: Medtronic Cardiovascular • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC