SEMINOMA

This study is testing whether two immunotherapy drugs, durvalumab and tremelimumab, can help patients whose germ cell tumors have returned or stopped responding to standard treatments. The trial is enrolling 30 adults with testicular, ovarian, or pineal gland tumors that have pro…

This trial is testing whether lower doses of chemotherapy and radiation can effectively treat a type of testicular cancer called seminoma. The goal is to control the cancer while reducing the risk of serious long-term side effects from standard, more intense treatments. It is for…

This study is testing whether the drug cabozantinib can help control advanced germ cell tumors that have stopped responding to standard chemotherapy. It will involve about 50 adults whose cancer has progressed despite previous treatments. Participants will take the oral medicatio…

This large national trial is testing whether a combination of two immunotherapy drugs (nivolumab and ipilimumab) can help control over 50 different types of rare cancers that have few or no standard treatment options. It enrolled over 800 adults whose rare cancers had progressed …

This study is for men with early-stage testicular cancer who have a higher risk of the cancer coming back. It compares two different single-dose chemotherapy treatments given after surgery to see which one is better at preventing a relapse. The goal is to find the treatment with …

This study is testing whether a specific substance in the blood (called miRNA 371) can help doctors predict if testicular cancer will return after initial treatment. Researchers are following 956 newly diagnosed patients for up to 3 years, collecting blood samples every few month…