SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS)
Clinical trials for SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS) explained in plain language.
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MS drug rituximab tested for brain and hand benefits in advanced patients
Disease control Recruiting nowThis study tests whether the drug rituximab can improve memory, thinking speed, and hand coordination in people with advanced secondary progressive multiple sclerosis (SPMS). About 46 participants with high disability will receive either rituximab or a placebo for one year. Resea…
Matched conditions: SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS)
Phase: PHASE2 • Sponsor: Cairo University • Aim: Disease control
Last updated May 26, 2026 04:02 UTC
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New pill could slow worsening disability in progressive MS
Disease control Recruiting nowThis study tests an experimental drug called remibrutinib in people with secondary progressive multiple sclerosis (SPMS), a form of MS where symptoms steadily worsen. The goal is to see if the drug can delay disability progression. About 1,275 adults aged 18-65 with SPMS will tak…
Matched conditions: SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS)
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 03:59 UTC
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New cell therapy TRX319 aims to slow progressive MS
Disease control Recruiting nowThis early-stage trial tests TRX319, a cell therapy, in 39 adults with primary or secondary progressive MS. The goal is to see if it is safe, find the best dose, and check if pre-treatment with another drug helps it work. Participants receive up to 3 doses over a year and undergo…
Matched conditions: SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS)
Phase: PHASE1, PHASE2 • Sponsor: Tr1X, Inc. • Aim: Disease control
Last updated May 04, 2026 16:21 UTC