SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS)
Clinical trials for SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS) explained in plain language.
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Drug trial aims to halt mental and physical decline in advanced MS
Disease control Recruiting nowThis study is testing whether the drug rituximab can help improve thinking skills and hand function in people with advanced secondary progressive multiple sclerosis (SPMS). Researchers will compare 46 participants with high disability—some receiving rituximab and some receiving a…
Matched conditions: SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS)
Phase: PHASE2 • Sponsor: Cairo University • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New MS therapy enters human testing
Disease control Recruiting nowThis early-stage study is testing a new therapy called TRX319 in adults with progressive forms of multiple sclerosis (MS). The main goals are to check if the treatment is safe, find the best dose, and see if a pre-treatment step is helpful. About 39 participants will be monitored…
Matched conditions: SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS)
Phase: PHASE1, PHASE2 • Sponsor: Tr1X, Inc. • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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Major trial aims to halt MS progression in its tracks
Disease control Recruiting nowThis large, late-stage study is testing whether an investigational drug called remibrutinib can slow or stop the worsening of disability in people with secondary progressive multiple sclerosis (SPMS). About 1,275 participants will be randomly assigned to receive either the drug o…
Matched conditions: SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (SPMS)
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Mar 16, 2026 15:27 UTC