SCHIZO AFFECTIVE DISORDER

This study aims to find the best weight-loss medication for people with bipolar disorder by matching drugs to specific obesity types (like 'hungry brain' or 'hungry gut'). About 100 adults aged 18-65 with bipolar or schizoaffective disorder and obesity will receive one of three F…

This study tests whether adding acetazolamide, a drug often used for altitude sickness, can reduce symptoms in people with schizophrenia that hasn't improved with standard treatments. About 60 adults aged 18-55 will receive either acetazolamide or a placebo alongside their usual …

This study tests whether adding cromoglicate, a drug used for allergies, can improve symptoms in people with schizophrenia or schizoaffective disorder. About 160 adults aged 18-60 who are already on a stable antipsychotic medication will receive either cromoglicate or a placebo f…

This study tests a virtual reality cognitive remediation program for people with psychotic disorders like schizophrenia. The program aims to improve thinking, social skills, and daily functioning. Researchers will enroll 52 adults aged 18-60 who are clinically stable. The main go…

This study compares a new, lower-energy seizure therapy (LAP-ST) to standard electroconvulsive therapy (ECT) for quickly reducing suicidal thoughts in people with depression, bipolar disorder, or schizoaffective disorder. The goal is to see if the new treatment works as well or b…

This study tests whether BXCL501 can safely reduce agitation in children aged 10-17 with schizophrenia or bipolar disorder. Participants receive either the drug or a placebo, and researchers measure changes in agitation using a standard rating scale. The trial is currently recrui…

This study looks at how the brain's earliest visual processing areas work in people with schizophrenia, bipolar disorder, or schizoaffective disorder. Researchers will use EEG (a non-invasive brain wave test) to measure electrical activity while participants view simple visual pa…

This study uses a safe, noninvasive brain stimulation technique called TMS to learn how hallucinations happen in people with schizophrenia or schizoaffective disorder. Researchers will measure brain activity and symptom changes in 68 participants before and after TMS. The goal is…

This study looks at whether a gentle, non-invasive brain stimulation technique called tDCS can improve the ability to recognize emotions on people's faces in those with schizophrenia. Researchers will use brain scans (fMRI) and brain wave recordings (EEG) to see how the brain res…