ROTATOR CUFF TEARS

This study tests whether a special graft made from donated placental tissue, called ActiveMatrix, can help the shoulder tendon heal better after rotator cuff repair surgery. About 72 people with a full-thickness tear in 1 or 2 tendons will be randomly assigned to get either a low…

This study tests whether adding a special scaffold called BioBrace® during rotator cuff surgery helps prevent the tendon from tearing again. About 268 adults aged 40–70 with full-thickness tears will be randomly assigned to get either standard repair or repair with the BioBrace® …

This study compares standard rotator cuff surgery to surgery plus a bioinductive patch that helps the tendon heal. About 78 adults with full-thickness tears will be followed for one year. The main goal is to see if the patch leads to fewer re-tears on ultrasound.

This study looks at 40 adults aged 50 to 75 with large rotator cuff tears. Half get standard surgery, and half get surgery plus a human skin patch. The goal is to see if the patch lowers the chance of the tendon tearing again one year later. Participants will have MRI scans and c…

This study compares two surgical options for people with large, irreparable rotator cuff tears: partial repair alone versus partial repair plus a tissue graft to rebuild the shoulder capsule. Researchers will track pain, function, and quality of life in 105 participants over two …

This study tests a new surgical approach for people with large rotator cuff tears. Doctors will use a special skin tissue (donated and processed to remove cells) combined with the patient's own bone marrow and shoulder lining cells to strengthen the repair. The goal is to see if …

This study tests a new device called FiberLocker® that reinforces rotator cuff surgery to help the tendon heal better. About 60 adults aged 30-70 with full-thickness tears will be enrolled. The main goal is to see if the repair heals properly on MRI after 6 months, with a focus o…

This study is checking the long-term safety and how well a medical device called the Pitch-Patch works for people who have had surgery for a torn rotator cuff in the shoulder. The Pitch-Patch is a small polyester patch that helps strengthen the repair. About 37 people who already…

This study looks at whether giving sex hormone therapy to men with low hormone levels can help their shoulder tendons heal better after surgery. About 58 men will receive either hormone pills or a placebo after rotator cuff repair. The goal is to see if the therapy improves tendo…

This study compares two surgeries for people with large, irreparable rotator cuff tears. One surgery smooths the bone (tuberoplasty), the other places a small balloon spacer under the shoulder. Researchers will track shoulder motion and pain relief in 40 adults to see which appro…

This study tests whether adding pain neuroscience education (PNE) to standard rehab improves pain, function, and fear of movement in 45 adults aged 40-75 recovering from rotator cuff tear surgery. Participants are randomly assigned to standard rehab alone, PNE before surgery, or …

This study looks at whether motor imagery training — mentally practicing movements without actually moving — can reduce pain, improve shoulder function, and lessen fear of movement in people with partial rotator cuff tears. About 80 adults will be randomly assigned to either stan…

This study looks at whether a digital platform called Band Connect helps people recovering from shoulder surgery or rotator cuff repair do their home exercises more consistently. About 500 adults aged 18 to 89 will use the platform, and researchers will track how many exercises t…

This study tests a hands-on therapy called Mobilization with Movement (MWM) for people with rotator cuff tears. 75 adults with shoulder pain for at least 3 months will be split into three groups: MWM, standard physical therapy, or a control group. Researchers will measure pain, f…

This study is looking at 104 people with shoulder problems to see if age-related muscle loss, called sarcopenia, is linked to the type and severity of rotator cuff tears. Participants will have their muscle strength and thigh thickness measured, and their shoulder MRIs will be re…

This study observes 60 adults having shoulder surgery to see how often a common numbing shot (interscalene block) temporarily paralyzes one side of the diaphragm. Participants are split into three groups receiving different numbing drugs or a catheter. The main goal is to measure…

This study follows 20,000 people who have had or will have shoulder replacement surgery to see how well the implants work over at least 10 years. Researchers will collect data on pain, daily activities, and strength using standard shoulder scores. The goal is to better understand…

This study is looking for genes that may increase the risk of rotator cuff tears, a common shoulder injury. Researchers will compare the DNA of 3,500 adults with and without confirmed tears on MRI. The goal is to better understand why some people get these tears and why recovery …