RESPIRATORY TRACT DISEASES

This study tested a booster vaccine for H5N6 bird flu in about 260 adults. Some had received a related H5N1 vaccine before, while others had not. The goal was to see if one or two booster shots were safe and could boost the body's immune defenses against the virus.

This study tested an investigational drug called vapendavir in 52 adults with COPD (a chronic lung disease). The goal was to see if vapendavir could reduce lower respiratory symptoms like cough, wheezing, and shortness of breath after they were exposed to a common cold virus (rhi…

This study looked at whether taking vitamin D every day can lower the risk of serious lung problems in children and teens with sickle cell disease. Lung issues like infections and acute chest syndrome are major causes of illness in this group. The study involved 58 participants a…

This study tested whether a simple checklist called the YEARS algorithm can safely rule out dangerous blood clots in the lungs (pulmonary embolism) in cancer patients, reducing the need for CT scans. Researchers compared the YEARS approach to standard CT scanning alone in 698 adu…

This study tested whether a one-week course of intravenous N-acetylcysteine (NAC) helps adults with respiratory diseases cough up thick mucus more easily. 333 hospitalized patients in China received either NAC, another drug (ambroxol), or a placebo. The results showed NAC was bet…

This study looked at 275 adults with a chronic cough and a lung condition called bronchiectasis, where airways are stretched and trap mucus. The goal was to better describe the physical features, lung scans, and bacteria in the lungs of people with unexplained bronchiectasis. Par…

This study looked at how much each millimeter of advancement of an oral appliance helps people with sleep apnea. Twenty adults with moderate or severe sleep apnea (who couldn't use a CPAP machine) took part. Researchers measured sleep apnea severity and tiredness at each step to …