Recurrent primary mediastinal large B-cell lymphoma
Clinical trials for Recurrent primary mediastinal large B-cell lymphoma explained in plain language.
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New combo therapy aims to boost immune attack on Hard-to-Treat lymphoma
Disease control PausedThis study tests whether adding an experimental drug (ST-067) to standard CAR T-cell therapy can safely and effectively treat adults with large B-cell lymphoma that has returned or not responded to prior treatments. About 33 participants will receive the combination to see if it …
Matched conditions: RECURRENT PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA
Phase 1/2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Immunotherapy duo takes on tough lymphomas
Disease control OngoingThis phase 2 trial tests whether adding varlilumab to nivolumab helps people with aggressive B-cell lymphomas that have returned or not responded to treatment. About 54 participants will receive either nivolumab alone or nivolumab plus varlilumab. The goal is to see if the combin…
Matched conditions: RECURRENT PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Experimental drug boosts Cancer-Killing cells in lymphoma trial
Disease control OngoingThis early-phase trial tests whether adding an experimental drug called NKTR-255 to standard CAR-T cell therapy can improve outcomes for people with large B-cell lymphoma that has returned or not responded to treatment. The study involves 27 adults and focuses on safety and how w…
Matched conditions: RECURRENT PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA
Phase 1 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:04 UTC