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Experimental combo aims to supercharge immune cells against Hard-to-Treat lymphoma

NCT ID NCT05359211

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 28 times

Summary

This early-phase trial tests whether adding an experimental drug (NKTR-255) to standard CAR-T cell therapy can improve outcomes for adults with large B-cell lymphoma that has returned or not responded to treatment. About 27 participants will receive the combination to see if it is safe and how well it works. The goal is to help the body's immune cells better recognize and kill cancer cells.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

Conditions

Explore the condition pages connected to this study.