RECURRENT MARGINAL ZONE LYMPHOMA
Clinical trials for RECURRENT MARGINAL ZONE LYMPHOMA explained in plain language.
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New drug duo aims to tame tough lymphomas
Disease control OngoingThis study is testing the safety and effectiveness of combining two drugs, nivolumab and lenalidomide, for patients with non-Hodgkin or Hodgkin lymphoma that has come back or stopped responding to other treatments. The goal is to see if using these drugs together can better contr…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: David Bond, MD • Aim: Disease control
Last updated Apr 04, 2026 04:50 UTC
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Scientists test Triple-Threat attack on Tough-to-Treat lymphomas
Disease control OngoingThis early-stage trial is testing a new combination of three drugs for people whose non-Hodgkin lymphoma has come back after previous treatment. The main goal is to find the safest and most effective dose of a new pill (PCI-32765) when given with two existing drugs (rituximab and…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Phase: PHASE1 • Sponsor: Kami Maddocks, MD • Aim: Disease control
Last updated Apr 04, 2026 04:50 UTC
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Early trial probes new drug cocktail for Tough-to-Treat lymphomas
Disease control OngoingThis early-stage study is testing the safety and best dose of a three-drug combination for patients with follicular or marginal zone lymphoma that has come back or not responded to prior treatment. The drugs—venetoclax, lenalidomide, and rituximab hyaluronidase—work together to h…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Phase: PHASE1 • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Scientists test re-engineered 'Living Drug' to hunt lymphoma
Disease control OngoingThis early-phase study is testing the safety and best dose of a personalized cell therapy for patients with aggressive B-cell lymphomas that have returned or are high-risk. The treatment involves collecting a patient's own immune cells (T cells), genetically modifying them in a l…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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New drug cocktail tested for aggressive lymphomas
Disease control OngoingThis early-stage study is testing a combination of three drugs—obinutuzumab, venetoclax, and lenalidomide—in patients whose B-cell non-Hodgkin lymphoma has come back or hasn't responded to previous treatments. The main goal is to find the safest and most effective dose of the dru…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Phase: PHASE1 • Sponsor: Beth Christian • Aim: Disease control
Last updated Apr 02, 2026 14:56 UTC
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New hope for patients when CAR-T fails: immunotherapy trial targets stubborn blood cancers
Disease control OngoingThis study is testing whether the immunotherapy drug nivolumab can help control blood cancers that have returned, stopped responding, or are still detectable after a patient has already received CAR-T cell therapy. It is for adults with specific types of lymphoma, leukemia, or mu…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New drug combo tested for Tough-to-Treat blood cancers
Disease control OngoingThis early-stage study is testing the safety and best dose of a new drug, pevonedistat, when given with an existing drug, ibrutinib. It is for adults with chronic lymphocytic leukemia or non-Hodgkin lymphoma that has come back or stopped responding to other treatments. The goal i…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Scientists re-engineer Patient's own cells to hunt down blood cancers
Disease control OngoingThis early-stage study is testing a new type of cellular immunotherapy for adults whose B-cell lymphoma or leukemia has come back. Doctors collect a patient's own immune cells, genetically modify them in a lab to better recognize and attack cancer cells, and then infuse them back…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Scientists test new drug duo in fight against stubborn lymphoma
Disease control OngoingThis early-stage study is testing the safety and best dose of two drugs, ibrutinib and lenalidomide, when given together. It is for adults whose B-cell non-Hodgkin lymphoma has come back or has not responded to previous treatments. The goal is to see if combining these drugs is s…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New drug combo tested to fight tough blood cancers
Disease control OngoingThis study is testing if adding a new drug called selinexor to the standard chemotherapy regimen (RCHOP) is safe and more effective for treating B-cell non-Hodgkin's lymphoma. It will first find the safest dose of the combination, then see how well it works for newly diagnosed pa…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Barbara Ann Karmanos Cancer Institute • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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New strategy aims to tame dangerous virus after cancer transplant
Disease control OngoingThis study is testing a personalized plan to manage cytomegalovirus (CMV), a common and potentially serious infection, in patients who have received a donor stem cell transplant for blood cancers or disorders. The plan involves closely monitoring the virus level and the patient's…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 16, 2026 15:26 UTC
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New 'Living Drug' trial offers hope for patients with aggressive lymphoma
Disease control OngoingThis study is testing a new type of personalized cell therapy for patients with B-cell non-Hodgkin lymphoma or chronic lymphocytic leukemia that has come back or not responded to standard treatments. Doctors take a patient's own immune cells, genetically modify them to better tar…
Matched conditions: RECURRENT MARGINAL ZONE LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Mar 05, 2026 13:59 UTC