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Engineered immune cells take on Hard-to-Treat blood cancers

NCT ID NCT02153580

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 29 times

Summary

This early-phase study tests a personalized cell therapy for adults with certain B-cell blood cancers that have returned after prior treatment. Doctors take a patient's own white blood cells, modify them in a lab to better recognize and attack cancer cells, and infuse them back after a short course of chemotherapy. The main goals are to check safety and find the best dose, while also monitoring how long the modified cells last in the body and whether the cancer shrinks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.