Engineered immune cells take on returning blood cancers in early trial

NCT ID NCT02153580

First seen Nov 01, 2025 · Last updated Apr 26, 2026 · Updated 28 times

Summary

This early-stage study tests a new treatment for people with certain B-cell blood cancers (like lymphoma or leukemia) that have returned after prior therapy. The treatment involves taking a patient's own white blood cells, adding a special gene to help them recognize and attack cancer cells, and giving them back after chemotherapy. The main goals are to check safety and find the best dose. The study enrolled 37 adults.

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Contacts and locations

Locations

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.