RECURRENT GLIOBLASTOMA
Clinical trials for RECURRENT GLIOBLASTOMA explained in plain language.
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New device may help chemotherapy reach deadly brain tumors
Disease control CompletedThis early-phase study tested whether a focused ultrasound device can safely open the blood-brain barrier in 13 patients with recurrent glioblastoma, a type of brain cancer. The goal was to allow the chemotherapy drug carboplatin to better reach the tumor. The study focused on sa…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: InSightec • Aim: Disease control
Last updated May 26, 2026 04:18 UTC
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Sound waves punch holes in brain's shield to let chemo attack deadly tumors
Disease control CompletedThis early-phase study tested whether a focused ultrasound device can safely and temporarily open the blood-brain barrier in 28 adults with recurrent glioblastoma, a type of brain cancer. The goal was to allow the chemotherapy drug carboplatin to better reach the tumor. The study…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: InSightec • Aim: Disease control
Last updated May 26, 2026 04:17 UTC
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Experimental combo targets recurrent brain tumors in early trial
Disease control CompletedThis early-phase study tested two drugs, ASP8374 and cemiplimab, in 14 people with a returning type of brain cancer called glioblastoma. The main goals were to find a safe dose and see if giving the drugs before surgery could boost the immune response against the tumor. The study…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 26, 2026 03:55 UTC
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Sound waves and radiation team up against returning brain tumors
Disease control CompletedThis small pilot study tested whether combining focused ultrasound with a second round of radiation is safe and helpful for people with recurrent glioblastoma, an aggressive brain cancer. Seven adults who had already tried standard treatments received the combination therapy as o…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: NA • Sponsor: NaviFUS Corporation • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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New dye could sharpen brain tumor detection on PET scans
Diagnosis CompletedThis study tested a special dye called fluoroethyltyrosine (FET) used in PET scans to see if it can better detect brain tumors that have come back. Researchers studied 143 people with different types of brain tumors. The goal was to see how well the dye helps doctors tell the dif…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Thomas Hope • Aim: Diagnosis
Last updated May 22, 2026 14:04 UTC
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Brain cancer pilot explores tailored drug cocktails
Knowledge-focused CompletedThis study tested whether it's possible to create and start personalized treatment plans quickly for adults with recurrent glioblastoma, a serious brain cancer. Researchers used a special genetic test on tumor tissue to find specific DNA changes and match patients to targeted dru…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1 • Sponsor: Jennifer Clarke • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC