RECURRENT GLIOBLASTOMA
Clinical trials for RECURRENT GLIOBLASTOMA explained in plain language.
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Sound waves open Brain's shield to attack deadly tumor
Disease control CompletedThis study tested whether a special focused ultrasound device could safely and temporarily open the protective blood-brain barrier in people with recurrent glioblastoma, a very aggressive brain cancer. The goal was to see if opening this barrier would help the chemotherapy drug c…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: InSightec • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Early trial tests new combo for tough brain cancer
Disease control CompletedThis early-stage study tested a new combination of two immunotherapy drugs, ASP8374 and cemiplimab, in adults with an aggressive brain tumor that had returned. The main goals were to find the safest dose of the drug combo and to see if giving it right before surgery changed the i…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Doctors test custom drug cocktails for tough brain cancer
Disease control CompletedThis small, early-stage study tested whether doctors could quickly design and start a personalized combination of up to four existing drugs for adults whose aggressive brain cancer (glioblastoma) had returned and could be surgically removed. Researchers analyzed the genetic makeu…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1 • Sponsor: Jennifer Clarke • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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Ultrasound 'Key' unlocks brain for chemo in tumor fight
Disease control CompletedThis study tested a new approach for treating recurrent glioblastoma, an aggressive brain cancer. Researchers used a focused ultrasound device to temporarily open the protective blood-brain barrier, aiming to help the chemotherapy drug carboplatin reach the tumor more effectively…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: InSightec • Aim: Disease control
Last updated Mar 06, 2026 15:37 UTC
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Sharper brain scan could tell real cancer from scar tissue
Diagnosis CompletedThis study tested a new type of PET scan that uses a special tracer called FET to see if it can better tell the difference between a brain tumor that has come back and harmless scar tissue from past treatment. It involved 143 people with brain tumors that were suspected of return…
Matched conditions: RECURRENT GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Thomas Hope • Aim: Diagnosis
Last updated Apr 04, 2026 02:20 UTC