RADIATION THERAPY

This study is for men with hormone-sensitive prostate cancer that has spread to a few places (up to 3 spots) in the bones or lymph nodes. It tests whether adding highly targeted radiation to those spots, on top of standard treatment, can delay the cancer from getting worse. About…

This study looks at whether adding a precise type of radiation called SABR to standard targeted therapy and immunotherapy can help people with kidney cancer that has come back or spread. The goal is to improve how long the cancer stays under control and possibly extend survival. …

This study tests whether adding a special type of PET/CT scan (CAIX-targeted) to standard treatment can help doctors precisely target and radiate kidney cancer that has spread. About 70 adults with recurrent or metastatic clear cell renal cell carcinoma will receive standard ther…

This study tests a new approach for people with a hard-to-treat type of colon cancer (pMMR/MSS). The treatment combines low-dose radiation (sparing lymph nodes), chemotherapy, and an immunotherapy drug (PD-1 inhibitor) before surgery. The goal is to see if this combination can ma…

This study tests whether a special PET/MRI scan can tell the difference between active tumor and harmless treatment-related changes in people with brain metastases. About 30 adults who have had radiation and are on immunotherapy will get a single 3-hour scan session. The goal is …

This study tests whether wearing a virtual reality (VR) headset during radiation therapy can help manage anxiety. About 54 adults with prostate, breast, lung, or head and neck cancer will try the VR device during their daily treatments. Researchers will measure how often patients…

This study tests whether a personalized activity coaching program can help women with endometrial cancer feel less tired during pelvic radiation therapy. Sixteen participants will receive coaching sessions to boost their energy and daily functioning. The goal is to see if this ap…

This study tests a special cooling mouthpiece used during radiation therapy for larynx cancer. The goal is to see if cooling the mouth can prevent or reduce taste loss, a common side effect of radiation. About 15 adults with advanced larynx cancer will try the device and report c…

This study tests whether artificial intelligence (AI) can help doctors outline the area to be treated with radiation for breast cancer. The goal is to see if AI-assisted outlining is as good as the current manual method and if it saves time. About 444 adults with breast cancer wi…

This study tests new ways to use MRI and CT scans to plan and monitor radiation therapy more effectively. It involves 837 adults who are already scheduled for radiation treatment. The goal is to improve imaging techniques, not to change the treatment itself.