PULMONARY FIBROSIS

This small pilot study looked at whether the drug pirfenidone is safe and helpful for people with a type of lung scarring (pulmonary fibrosis) linked to a specific antibody called anti-MPO. The study included 7 adults with this condition. Researchers measured lung function change…

This study tested whether the drug nintedanib can slow lung scarring in people who had COVID-19 and still have lung problems more than 30 days later. 103 adults who needed oxygen or had low oxygen levels took part. The goal was to see if the drug helps preserve lung function over…

This study tested a single infusion of stem cells from donated umbilical cord tissue in people with severe scleroderma that also affects the lungs. The goal was to see if the treatment could improve lung function, exercise ability, and quality of life. Only one person took part, …

This study tested an experimental drug called BMS-986278 in 403 adults with pulmonary fibrosis, a condition that causes lung scarring and breathing problems. The goal was to see if the drug could improve lung function and check for side effects. Participants took the drug or a pl…

This early-stage study tested a single dose of a new drug called 9MW3811 in 32 healthy adults to see if it is safe and how the body processes it. The drug is being developed for lung scarring (pulmonary fibrosis) and tumors, but this study did not involve patients with those cond…

This study looked at how shortness of breath changes over 6 months in 51 people with idiopathic pulmonary fibrosis (IPF), a lung scarring disease. Researchers measured both the physical sensation and emotional impact of breathlessness using questionnaires. The goal was to better …

This early-stage study tested an inhaled drug called CHF10073 in 155 healthy volunteers to see if it is safe and how the body processes it. The study also checked how another drug, itraconazole, affects CHF10073 levels. The goal was to gather safety information before testing the…

This study looked at the genetics of a rare lung condition called combined pulmonary fibrosis and emphysema (CPFE) syndrome, which causes both scarring and air sac damage. Researchers compared 250 participants, including patients with CPFE, those with only scarring or only emphys…

This study followed 38 adults who survived severe H1N1 flu that caused lung failure. Researchers compared those who needed a machine to add oxygen to their blood with those who did not. They measured lung function, quality of life, and mental health at least 9 months after leavin…