PULMONARY FIBROSIS

This small study tested whether a drug called pirfenidone could safely slow the progression of lung scarring (pulmonary fibrosis) in patients who also have a specific immune system marker or related blood vessel inflammation. The trial involved 7 adults with this specific conditi…

This study tested whether an experimental drug called BMS-986278 could help people with pulmonary fibrosis, a condition that causes scarring in the lungs. 403 participants were randomly assigned to receive either the drug or a placebo for 26 weeks to see if it could slow the decl…

This study aimed to understand the long-term health of people who survived a severe lung injury from the 2009 H1N1 flu. Researchers compared two groups: those who needed a life-support machine for their lungs and those who did not. They checked lung capacity, quality of life, and…

This was the first study in humans to test the safety of an experimental drug called 9MW3811. The trial involved 32 healthy adult volunteers who received either the drug or a placebo. Researchers measured how the body processed the drug and checked for any side effects to determi…

This study aimed to understand the genetic factors behind Combined Pulmonary Fibrosis and Emphysema (CPFE), a severe lung disease mostly affecting smokers. Researchers compared 250 people, including patients with CPFE, other lung conditions, and healthy individuals, to see if tho…

This early-stage study tested the safety and how the body processes an inhaled drug called CHF10073, which is being developed for pulmonary fibrosis (lung scarring). It involved 155 healthy volunteers to check for side effects and measure drug levels in the blood and lungs. The m…