PSORIATIC ARTHRITIS (PSA)

This study is testing a live attenuated dengue vaccine (Butantan-DV) in people aged 12–59 with autoimmune rheumatic diseases like rheumatoid arthritis or lupus, who are stable and on low or no immune-suppressing drugs. Researchers want to see if the vaccine is safe and triggers a…

This study compares two common treatments—methotrexate and a TNF inhibitor (adalimumab biosimilar)—to see which better prevents joint damage in people with early psoriatic arthritis (PsA). About 108 adults with active PsA for less than 2 years will be randomly assigned to one of …

This study tests whether people with rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis who are doing well on a JAK inhibitor can safely lower their dose without losing disease control. About 200 participants will either follow a guided dose-reduction plan or c…

This study compares two ways to find psoriatic arthritis (PsA) in people with psoriasis: a questionnaire filled out by the patient versus a physical exam by a dermatologist. About 500 adults with psoriasis will be checked using both methods, then referred to a rheumatologist for …

This study is testing a new blood test that may help doctors choose the most effective medicine for people with rheumatic diseases like rheumatoid arthritis, lupus, and vasculitis. Researchers will take a blood sample and use it to see how a person's immune cells react to differe…

This early-stage study tests a new oral drug, LPX-TI641, in 48 adults with rheumatoid arthritis or psoriatic arthritis. The main goal is to see if the drug is safe and tolerable compared to a placebo over 28 days. Researchers will also measure how the drug moves through the body.…

This study looks at how weight loss (using tirzepatide) and a biologic drug (ixekizumab) change the skin, joint, and fat tissues in people with psoriatic arthritis who are overweight or obese. About 45 adults will take one or both treatments for 12 weeks, with tissue and blood sa…

This study looks at 200 adults with autoimmune joint diseases like rheumatoid arthritis and psoriatic arthritis. Researchers will measure markers of oxidative stress in their blood at three visits over one year. The goal is to see if these markers can help track disease progressi…

This study looks at the link between nutrition and disease activity in people with rheumatic diseases like rheumatoid arthritis, lupus, and psoriatic arthritis. Researchers will assess the nutritional status of 460 participants using several standard tools and compare it to how a…

This study collects health information from up to 10,000 people with conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a phone app to share symptoms, wearables data, and lifestyle details. The goal is to help researchers better understand these illness…

This study follows 700 adults with axial spondyloarthritis or psoriatic arthritis who have just started a new medication (bimekizumab, upadacitinib, risankizumab, guselkumab, or a TNF inhibitor) at UK hospitals. Researchers will review medical records and ask patients to complete…

This study follows 425 adults with recent psoriatic arthritis (PsA) for up to 10 years. The goal is to understand why some people develop lasting joint damage while others do not. By tracking X-rays, genetics, and other factors, researchers hope to find early signs of aggressive …