PRURITUS

This small study tests whether gentle neck traction (a type of stretching) can help people with nerve-related itching on the scalp, arms, or upper back use less medication. Twelve adults who already take gabapentin or pregabalin for itch will try daily home traction for 12 weeks.…

This study tests if dupilumab can reduce severe itching in adults with chronic pruritus of unknown origin (CPUO) — a condition where people itch for months with no clear cause. About 284 adults aged 18 to 90 will receive either dupilumab or a placebo for 24 weeks, alongside stand…

This study tests whether a relaxation technique called progressive muscle relaxation (PMR) works better when combined with virtual reality (VR) for burn survivors. About 34 adults who have had a burn injury for at least 6 months and still have symptoms like pain, itch, or sleep p…

This study tests if a medicine called difelikefalin is safe for teenagers aged 12 to 17 who have severe itching due to kidney disease and are on dialysis. All 18 participants will receive the medicine during their regular dialysis visits for up to 12 weeks. The goal is to see if …

This study looks at how often and how long itching occurs in people with drug-induced liver injury (DILI). Researchers will follow 50 adults with DILI and compare them to people with other liver conditions. The goal is to better understand itching in DILI and lay the groundwork f…