PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY
Clinical trials for PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY explained in plain language.
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Experimental drug aims to restore immune defenses against fatal brain virus
Disease control CompletedThis early-phase study tested a drug called NT-I7 in 12 adults with progressive multifocal leukoencephalopathy (PML), a rare and serious brain infection caused by a virus. The goal was to see if NT-I7 could increase the number of infection-fighting white blood cells (lymphocytes)…
Matched conditions: PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY
Phase: EARLY_PHASE1 • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Disease control
Last updated May 26, 2026 02:51 UTC
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Could donor immune cells beat a rare brain infection?
Disease control CompletedThis early-phase study tested whether giving special immune cells (PyVST) from a healthy relative could safely treat progressive multifocal leukoencephalopathy (PML), a serious brain infection in people with weakened immune systems. Sixty adults with PML received up to three infu…
Matched conditions: PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY
Phase: EARLY_PHASE1 • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Disease control
Last updated May 20, 2026 11:58 UTC
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Scientists probe immune 'Brakes' in rare brain virus
Knowledge-focused CompletedThis study looked at 22 people with a rare brain infection called PML, which affects those with weak immune systems. Researchers measured certain signals on immune cells (T cells) to see if they are linked to how well the body fights the virus. The goal was to gather information …
Matched conditions: PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC