PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Clinical trials for PROGNOSTIC STAGE III BREAST CANCER AJCC V8 explained in plain language.
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New vaccine aims to train immune system to fight triple negative breast cancer
⭐️ VACCINE ⭐️ OngoingThis study tests a DNA-based vaccine called STEMVAC in 33 people with early-stage triple negative breast cancer. The vaccine targets proteins found on breast cancer stem cells and aims to train the immune system to recognize and destroy these cells. The main goal is to see if the…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 09, 2026 12:08 UTC
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Radiation before breast surgery may improve results
Disease control OngoingThis study tests whether giving an extra dose of radiation (a boost) before breast cancer surgery is safe and helpful. About 103 people with early-stage breast cancer that hasn't spread will receive the boost, then standard radiation and surgery. The goal is to see if this approa…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Jun 22, 2026 12:09 UTC
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Double-Drug attack aims to stop HER2+ breast cancer relapse
Disease control OngoingThis phase 3 trial tests whether adding tucatinib to standard T-DM1 therapy works better than T-DM1 alone at preventing breast cancer from coming back. About 1,056 patients with HER2-positive breast cancer who still have cancer cells after initial treatment will take part. The st…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 22, 2026 12:00 UTC
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New drug combo targets BRCA cancers in early trial
Disease control OngoingThis early-phase study tests a combination of two drugs, niraparib and dostarlimab, in 18 adults with BRCA-mutated breast, pancreas, or ovary cancer that has spread or cannot be surgically removed. Niraparib blocks a DNA repair protein in cancer cells, while dostarlimab helps the…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 16, 2026 12:51 UTC
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New targeted therapy combo shows promise for HER2+ breast cancer
Disease control OngoingThis study tests a combination of targeted drugs (ribociclib, tucatinib, trastuzumab, with or without fulvestrant) for HER2-positive breast cancer. In the first part, it looks at safety in patients whose cancer has spread. In the second part, it compares these drugs to standard c…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Texts and calls boost breast cancer Pill-Taking in major trial
Disease control OngoingThis study tests whether adding text message reminders and/or telephone counseling helps breast cancer patients take their daily hormone therapy pills more consistently. About 1,167 women with early-stage, hormone-sensitive breast cancer will be followed for up to two years. The …
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 12, 2026 12:04 UTC
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New web tool aims to ease symptoms for young breast cancer survivors
Symptom relief OngoingThis study tests a web-based portal called YES (Young, Empowered & Strong) designed to help adolescent and young adult breast cancer survivors monitor and manage their symptoms. Researchers will compare the quality of life of 400 women who use the portal to those receiving standa…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 23, 2026 11:59 UTC
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Writing away the pain: new study tests expressive writing for chinese breast cancer survivors
Symptom relief OngoingThis study looks at whether a culturally tailored writing program can improve the well-being of Chinese immigrant women who had breast cancer (stages 0 to III). About 256 women who finished their main cancer treatment in the last 5 years will write about their experiences. The go…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 22, 2026 12:05 UTC
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Walking through chemo: new study tests exercise for older breast cancer patients
Symptom relief OngoingThis study looks at whether a regular exercise program is practical for women aged 65 and older who are receiving chemotherapy for early-stage breast cancer. Participants will be asked to walk and do arm exercises several times a week. The goal is to see if exercise can reduce th…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 17, 2026 12:07 UTC
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New study tracks shoulder pain after breast cancer radiation
Knowledge-focused OngoingThis study looks at shoulder and arm problems in breast cancer patients with lymph node involvement who receive radiation therapy. About 61 participants will be followed for one year after treatment to see how often they have lasting shoulder issues. The goal is to understand whi…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:08 UTC
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Cancer survivors share fertility hopes in new survey
Knowledge-focused OngoingThis study surveys women aged 18-45 who have had gynecological or breast cancer to learn how they think about having a baby after cancer. Researchers will use the results to help future patients make informed decisions about treatment and family planning. About 1,410 participants…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:06 UTC
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Can we predict who will get nerve damage from chemo?
Knowledge-focused OngoingThis study aims to find out why some cancer patients develop nerve damage (tingling or numbness in hands and feet) from taxane chemotherapy. Researchers will track over 1,300 people with breast, lung, or ovarian cancer to see how age, gender, and other factors affect their risk. …
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:53 UTC
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Genetic test may predict who gets nerve pain from breast cancer chemo
Knowledge-focused OngoingThis study looks at whether certain genes make African American women with breast cancer more likely to develop nerve damage (pain, numbness, tingling) from common chemotherapy drugs called taxanes. About 249 women with stage I-III breast cancer will receive either docetaxel or w…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:49 UTC
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New study aims to help older breast cancer patients make chemotherapy choices
Knowledge-focused OngoingThis study looks at how women aged 65 and older with early-stage breast cancer decide whether to have chemotherapy before or after surgery. Researchers will use surveys to understand their needs and then create a tool to help patients and doctors make better, shared decisions. Th…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:49 UTC
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Gene test may guide breast cancer therapy choices
Knowledge-focused OngoingThis study looks at whether a genetic test on tumor samples can predict how well HER2-negative breast cancer will respond to standard treatments like chemotherapy or hormone therapy. About 1,100 people with stage I-III breast cancer are taking part. The goal is to see if this tes…
Matched conditions: PROGNOSTIC STAGE III BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:48 UTC