Primary biliary cholangitis (PBC)
Clinical trials for Primary biliary cholangitis (PBC) explained in plain language.
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New drug combo shows promise for rare liver disease in early trial
Disease control CompletedThis early-phase study tested whether adding fenofibrate to standard treatment (ursodeoxycholic acid) helps people newly diagnosed with primary biliary cholangitis, a chronic liver disease. Thirty adults participated to see if the combination could normalize liver enzyme levels a…
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Early phase 1 • Sponsor: Han Ying • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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New nanoparticle therapy tested for autoimmune liver disease – first human trial complete
Disease control CompletedThis first-in-human study tested a single dose of PVT201, a nanoparticle-based drug, in 24 people: healthy volunteers and patients with primary biliary cholangitis (PBC) or primary sclerosing cholangitis (PSC). The main goal was to check safety and how the drug moves through the …
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Phase 1 • Sponsor: Parvus Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Can breathing and meditation ease PBC symptoms? new study says maybe.
Symptom relief CompletedThis study tested a 10-week online wellness program for women with primary biliary cholangitis (PBC), a chronic liver disease that causes fatigue, itching, brain fog, and emotional distress. The program included guided breathing, meditation, gentle movement, and optional nutritio…
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Can a T-Cell signature unlock the secrets of autoimmune liver disease?
Knowledge-focused CompletedThis study aims to identify the unique molecular signature of immune cells called T cells that mistakenly attack the liver in autoimmune liver diseases like autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis. Researchers will analyze blood sampl…
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC