PRIMARY BILIARY CHOLANGITIS (PBC)
Clinical trials for PRIMARY BILIARY CHOLANGITIS (PBC) explained in plain language.
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New hope to halt deadly liver disease progression
Disease control Recruiting nowThis study is testing if a daily pill called elafibranor can slow down the worsening of primary biliary cholangitis (PBC), a serious liver disease that can lead to liver failure, transplant, or death. It will compare the drug to a placebo in about 276 adults who already have live…
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Phase: PHASE3 • Sponsor: Ipsen • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New hope for Long-Term liver disease control
Disease control Recruiting nowThis study aims to check the long-term safety of a two-drug combination (fenofibrate plus ursodeoxycholic acid) for people with Primary Biliary Cholangitis (PBC), a chronic liver disease. It will follow 300 participants who have already been in related studies to see how well the…
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Phase: PHASE3 • Sponsor: Xijing Hospital of Digestive Diseases • Aim: Disease control
Last updated Mar 13, 2026 15:05 UTC
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Massive study aims to predict survival for liver disease patients
Disease control Recruiting nowThis study is observing 3000 patients in China with Primary Biliary Cholangitis (PBC), a chronic liver disease. Researchers want to see if patients who have a better response to standard medication, shown by improved liver blood tests, live longer without serious complications li…
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Sponsor: RenJi Hospital • Aim: Disease control
Last updated Mar 11, 2026 14:52 UTC
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Doctors test Long-Term safety of liver disease drug duo
Disease control Recruiting nowThis study aims to check the long-term safety of using two medications, fenofibrate and ursodeoxycholic acid, together in people with Primary Biliary Cholangitis (PBC), a chronic liver disease. It will enroll about 150 adults who have already completed a related earlier study. Th…
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Phase: PHASE3 • Sponsor: Xijing Hospital of Digestive Diseases • Aim: Disease control
Last updated Mar 10, 2026 12:53 UTC
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New hope for untreated liver disease patients in major trial
Disease control Recruiting nowThis study is testing if the drug fenofibrate works better than the current standard treatment (UDCA) for adults with primary biliary cholangitis (PBC), a chronic liver disease. Participants who haven't had previous treatment will take either fenofibrate or UDCA daily for a year,…
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Phase: PHASE3 • Sponsor: Xijing Hospital of Digestive Diseases • Aim: Disease control
Last updated Mar 04, 2026 15:29 UTC
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Searching for hidden liver disease before symptoms appear
Diagnosis Recruiting nowThis study aims to find better ways to diagnose a liver disease called Primary Biliary Cholangitis (PBC) very early, before standard blood tests show problems. Researchers will study 80 adults who have positive antibodies for PBC but normal liver enzyme levels. Participants will …
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Sponsor: Hospital Universitario La Paz • Aim: Diagnosis
Last updated Mar 24, 2026 12:01 UTC
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New hope for PBC 'Brain Fog': supervised exercise program aims to tackle debilitating fatigue
Symptom relief Recruiting nowThis study is testing if a special program of supervised exercise, nutritional advice, and psychological support can reduce the severe fatigue that affects many people with primary biliary cholangitis (PBC). Researchers will enroll 64 adults with PBC and significant fatigue to se…
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Phase: NA • Sponsor: Hospital Clinic of Barcelona • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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New drug trial targets debilitating fatigue and brain fog in liver disease
Symptom relief Recruiting nowThis study is testing a new drug called golexanolone to see if it can help people with a liver disease called Primary Biliary Cholangitis (PBC) who suffer from severe fatigue and cognitive problems like brain fog. Researchers will compare two different doses of the drug against a…
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Phase: PHASE1, PHASE2 • Sponsor: Umecrine Cognition AB • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Massive 4000-Patient study launched to map rare liver disease in china
Knowledge-focused Recruiting nowThis study aims to better understand primary biliary cholangitis (PBC), a chronic autoimmune liver disease, in China. Researchers will follow 4,000 patients from multiple hospitals to track their symptoms, treatments, and long-term health outcomes. The goal is to gather detailed …
Matched conditions: PRIMARY BILIARY CHOLANGITIS (PBC)
Sponsor: Beijing Friendship Hospital • Aim: Knowledge-focused
Last updated Feb 25, 2026 15:07 UTC