New combo therapy aims to tame rare liver disease in Long-Term trial

NCT ID NCT06755541

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests the long-term safety of combining fenofibrate with standard treatment (ursodeoxycholic acid) in 150 adults with primary biliary cholangitis, a chronic liver disease. Participants previously completed a related study and will take fenofibrate capsules daily. Researchers will monitor side effects, deaths, liver transplants, and liver enzyme levels to see if the combination is safe and tolerable over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fenofibrate and ursodeoxycholic acid

What this could lead to

If it works, this could provide a safe long-term treatment option to help control PBC and reduce the need for liver transplants.

What could go wrong

This is an open-label study with no placebo group, so results may be less reliable. Side effects from fenofibrate are possible, and it may not improve outcomes for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

primary biliary cholangitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Xijing hospital

    RECRUITING

    Xi'an, Shaanxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••