Preterm labor
Clinical trials for Preterm labor explained in plain language.
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Which drug stops preterm labor best? new study pits progesterone against nifedipine
Disease control CompletedThis study tested two common drugs—vaginal progesterone and oral nifedipine—to see which works better at delaying preterm labor in 160 pregnant women aged 18-35 with a single baby. The goal was to prevent delivery within 48 hours or before 37 weeks. Results could help doctors cho…
Matched conditions: PRETERM LABOR
Phase 4 • Sponsor: Dr Mudassar Saeed Pansota • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New test may improve preterm birth prediction
Diagnosis CompletedThis study tested a new combination test called Premaquick, which measures three markers in vaginal fluid, to see if it can better predict whether a woman with threatened preterm labor will deliver within 7 days. Researchers compared it to the standard fetal fibronectin test in 2…
Matched conditions: PRETERM LABOR
Sponsor: University Hospital, Clermont-Ferrand • Aim: Diagnosis
Last updated Jun 27, 2026 12:02 UTC
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New ultrasound technique may predict lung problems in preterm infants
Diagnosis CompletedThis study looked at whether a special ultrasound technique called fetal lung elastography can predict respiratory distress syndrome (RDS) in preterm babies. Researchers measured lung stiffness in 80 unborn babies between 24-33 weeks of pregnancy and compared those who later deve…
Matched conditions: PRETERM LABOR
Sponsor: Ankara Etlik City Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 11:02 UTC
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Fish oil may protect babies of moms who smoke
Prevention CompletedThis study looked at whether omega-3 supplements (fish oil) could help pregnant women who smoke have healthier pregnancies and possibly smoke less. About 237 pregnant smokers took either omega-3 pills or a placebo. The goal was to see if the supplements could reduce preterm labor…
Matched conditions: PRETERM LABOR
Phase 2 • Sponsor: Vanderbilt University Medical Center • Aim: Prevention
Last updated Jun 27, 2026 13:03 UTC
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Progesterone or pessary: which prevents preterm birth better?
Prevention CompletedThis study tested whether natural progesterone or a cervical pessary (a silicone ring placed in the vagina) is better at preventing early birth in pregnant women with a short cervix (25 mm or less). The trial included 203 women with a single baby. Researchers tracked how many gav…
Matched conditions: PRETERM LABOR
Phase 4 • Sponsor: University of Sao Paulo • Aim: Prevention
Last updated Jun 27, 2026 11:02 UTC
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Can a gentle air puff help preterm babies breathe and sleep better?
Symptom relief CompletedThis pilot study is testing whether a device called a 'scare ventilator' can help preterm babies breathe more regularly and sleep better. Ten healthy preterm babies will be observed for two hours without the device, then for two hours with the device set at 20 air puffs per minut…
Matched conditions: PRETERM LABOR
Sponsor: Pontificia Universidad Catolica de Chile • Aim: Symptom relief
Last updated Aug 28, 2026 00:00 UTC
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Ultrasound may reveal how steroids shape the fetal brain
Knowledge-focused CompletedThis pilot study asks whether 2D and 3D ultrasound can reliably measure fetal and newborn brain growth in pregnancies affected by threatened preterm labor and corticosteroid treatment. Researchers will compare ultrasound images from two groups of pregnant people: those who receiv…
Matched conditions: PRETERM LABOR
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Could hidden bacteria be behind early births?
Knowledge-focused CompletedThis study looks at whether certain bacteria that produce an enzyme called phospholipase A2 are linked to preterm labor. It also compares pregnant teens and adults to see if teens are more likely to carry these bacteria and have different immune markers. The goal is to better und…
Matched conditions: PRETERM LABOR
Sponsor: CAMC Health System • Aim: Knowledge-focused
Last updated Aug 23, 2026 00:00 UTC
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New ultrasound combo may spot preterm labor earlier
Knowledge-focused CompletedThis study looks at whether adding a measurement of the angle between the uterus and cervix to a standard ultrasound can help predict preterm labor. Researchers will study 47 pregnant women between 24 and 34 weeks who show early signs of labor. The goal is to see if combining the…
Matched conditions: PRETERM LABOR
Sponsor: Kafrelsheikh University • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC
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Scientists probe cellular signals that may trigger early labor
Knowledge-focused CompletedThis study investigates whether a set of genes and proteins called the Hippo-YAP pathway, along with related microRNAs, are involved in preterm birth. Researchers analyzed blood, placenta, and uterine tissue from women who had cesarean deliveries either at full term or after spon…
Matched conditions: PRETERM LABOR
Sponsor: Cumhuriyet University • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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Protein levels in blood may shed light on preterm birth risk
Knowledge-focused CompletedThis study looked at a protein called osteopontin in the blood of pregnant women whose water broke too early (PPROM). Researchers compared 71 women with early rupture to those with normal-term rupture to see if protein levels differ. The goal was to learn more about the biology b…
Matched conditions: PRETERM LABOR
Sponsor: Batman Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC