Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Progesterone or pessary: which prevents preterm birth better?

NCT ID NCT02511574

Prevention Sponsor: University of Sao Paulo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether natural progesterone or a cervical pessary (a silicone ring placed in the vagina) is better at preventing early birth in pregnant women with a short cervix (25 mm or less). The trial included 203 women with a single baby. Researchers tracked how many gave birth before 34 weeks. The goal is to find the most effective way to reduce preterm births and improve newborn health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
natural progesterone (drug) and cervical pessary (device)
What this could lead to
If one option proves clearly better, it could become the standard way to prevent preterm birth in women with a short cervix, reducing health risks for babies.
What could go wrong
This is a single completed study with 203 participants, so results may not apply to all pregnant women. Neither treatment is a guarantee, and some women may still deliver early.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

203 people

The number who actually took part.

Started

Aug 2015

Finished

Aug 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * gestational age between 20 weeks and 23 weeks and 6 days * singleton pregnancies Exclusion Criteria: * fetal death at randomization * major structural or chromosomal abnormality * cervical cerclage in the current pregnancy * preterm rupture of membranes diagnosed before randomization

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Premature birth are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Obstetric Labor, Premature Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Premature birth Preterm labor

Contacts and locations

Locations

  • Hospital das Clínicas da Faculdade de Medicina da USP

    São Paulo, São Paulo, 05403-000, Brazil

More trials for these conditions

Other studies related to the condition(s) this trial covers.