POST-TRAUMATIC STRESS DISORDER (PTSD)

This study tests whether a slow-release form of melatonin can improve sleep in 120 children and teens (ages 2–17.5) with PTSD who have trouble sleeping. Participants will receive either melatonin or a placebo for 13 weeks. The goal is to see if melatonin increases total sleep tim…

This study tests a digital therapy that combines unconscious exposure to trauma-related images with bilateral eye movements to reduce intrusive memories in people with PTSD. About 123 participants who experience at least 5 intrusive memories per week will be randomly assigned to …

This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can reduce PTSD symptoms in adults who have survived intimate partner violence. 76 participants will receive either a high or low dose and complete weekly th…

This study tests a new way to reduce intrusive memories in people with PTSD. Instead of asking people to recall their trauma, researchers use a brief, unconscious reminder followed by playing the video game Tetris. The goal is to see if this approach can lower the number of upset…

This Phase 2 study will test whether inhaling high-THC cannabis (18-22% THC) can reduce PTSD symptoms in 320 U.S. veterans compared to a placebo with less than 1% THC. Participants will be randomly assigned to one of two groups in a double-blind design, and researchers will measu…

This study tests a therapy called CFTSI for children aged 7 to 17 who have experienced a traumatic event in the last 3 months. The goal is to see if CFTSI reduces post-traumatic stress symptoms better than standard supportive therapy. 140 children and their families will take par…

This study tests a new, intensive brain stimulation program for 30 Canadian veterans who have both PTSD and chronic pain. Over one week, participants receive 5-6 daily sessions of a 3-minute magnetic pulse treatment called iTBS. Researchers will check if symptoms improve right af…