PLEURAL EFFUSION

This study tests whether giving enzyme medications once a day through a chest tube works as well as the standard twice-a-day schedule for treating serious lung infections (pleural infections). About 270 adults hospitalized with infected fluid around the lung will be randomly assi…

This study tests whether an AI tool helps doctors find lung issues like pneumonia or fluid buildup on chest X-rays more accurately than doctors working alone. About 1,470 adults with breathing problems will have their X-rays read with and without AI support. The goal is to see if…

This study tests a new portable chest X-ray machine that takes moving images (15 frames per second) right at the bedside in the ICU. Researchers want to see if it gives doctors better information about lung and diaphragm function compared to standard X-rays. About 230 adults with…

This study tests whether using a special real-time microscope (confocal laser endomicroscopy) during a lung lining biopsy helps doctors diagnose unknown pleural disease more accurately than standard visual guidance. About 158 adults with unexplained fluid buildup around the lungs…

This study looks at whether using a smaller chest drain (16F) instead of the standard larger one (24F) reduces pain after minimally invasive lung surgery. About 124 adults with operable lung cancer will be randomly assigned to one of the two drain sizes. Pain levels will be measu…

This study looks at 200 cancer patients with fluid buildup around the lungs (malignant pleural effusion). It compares two ways to drain the fluid—using gravity or a vacuum bottle—to see which causes less chest pain. The goal is to find a method that improves comfort and quality o…

This study looks at two breathing exercise methods to help children aged 5–16 who have fluid around their lungs (pleural effusion). One group will use a simple bubble-blowing device with special breathing techniques, while the other uses a standard incentive spirometer. Both grou…

This study tests whether using virtual reality (VR) goggles during a chest drain procedure can make patients more comfortable and satisfied. About 80 adults needing a chest drain will be randomly assigned to receive the procedure with or without VR distraction. The goal is to see…

This study looks at fluid from around the lungs (pleural effusion) to find new markers that could help diagnose lung adenocarcinoma. Researchers will compare samples from 100 patients with and without cancer. The goal is to see if these markers can make diagnosis easier and more …

This study compares two procedures—thoracentesis (draining fluid) and pleuroscopy (taking a tissue sample)—to see which one gives a clearer diagnosis faster for people with fluid around the lungs that may be caused by cancer. About 98 adults with suspected cancer will be randomly…

This study looks at whether using a heparin lock after flushing with normal saline keeps small chest tubes (used to drain fluid from around the lungs) from getting blocked better than flushing alone. About 40 adults with pleural effusion will take part. The goal is to find the be…