PERICARDITIS

This study tests an injected drug called KPL-387 in 165 people with recurrent pericarditis, a condition where the sac around the heart becomes inflamed again and again. The goal is to see if KPL-387 can reduce flare-ups and pain better than a placebo. Participants must have sympt…

This study tests if a new drug called KPL-387 can safely replace standard treatments for people with recurrent pericarditis (repeated heart lining inflammation). About 80 adults whose condition is well-controlled on current therapy will switch to KPL-387 alone. Researchers will t…

This study tests whether a special vest called HALD can accurately record heart and lung sounds during a routine clinic visit. Researchers will compare the vest's recordings to what doctors hear during a physical exam. The goal is to see if the vest is easy to use and comfortable…

This study is gathering information from up to 15 people with CACP syndrome, a rare genetic condition that causes joint stiffness, hip problems, and sometimes heart inflammation. Researchers want to better understand how the disease progresses and how it is currently managed. The…

This study aims to learn how well heart scans (MRI, ultrasound, PET) can detect and predict outcomes in people with suspected or known inflammatory heart diseases. Researchers will follow 5,000 adults for one year to see how often heart involvement is confirmed and how it affects…

This study looks at people who developed heart inflammation (myocarditis or pericarditis) after getting a COVID-19 vaccine. Researchers will review medical records and follow up with 400 participants for up to 4 years to understand long-term health effects. The goal is to learn m…