New drug aims to stop recurring heart lining pain

NCT ID NCT07010159

Recruiting now Disease control Sponsor: Kiniksa Pharmaceuticals International, plc Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 29 times

Summary

This study tests a new medicine called KPL-387 for people who have repeated episodes of pericarditis, a painful inflammation of the lining around the heart. The goal is to see if the drug can reduce flare-ups and pain in patients who still have symptoms despite using standard treatments. About 165 adults will take part in this phase 2/3 trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Investigational Site 001
WITHDRAWN

Columbus, Georgia, 31904, United States
Investigational Site 002
WITHDRAWN

Overland Park, Kansas, 66221, United States
Investigational Site 003
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Cleveland, Ohio, 44195, United States
Investigational Site 004
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Chicago, Illinois, 60611, United States
Investigational Site 005
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Austin, Texas, 78705, United States
Investigational Site 006
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Charlottesville, Virginia, 22903, United States
Investigational Site 007
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Milan, 20157, Italy
Investigational Site 008
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San Francisco, California, 94158, United States
Investigational Site 009
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Cincinnati, Ohio, 45219, United States
Investigational Site 010
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Barcelona, 8035, Spain
Investigational Site 011
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Murcia, 30120, Spain
Investigational Site 012
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Rochester, Minnesota, 55905, United States
Investigational Site 013
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Houston, Texas, 77030, United States
Investigational Site 014
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Indianapolis, Indiana, 46184, United States
Investigational Site 015
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New York, New York, 10016, United States
Investigational Site 016
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Westminster, Colorado, 80023, United States
Investigational Site 017
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Southampton, SO17 1BJ, United Kingdom
Investigational Site 018
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Gilbert, Arizona, 85297, United States
Investigational Site 019
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Poitiers, 86000, France
Investigational Site 020
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London, EC1A 7BE, United Kingdom
Investigational Site 021
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Paris, 75013, France
Investigational Site 022
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New York, New York, 10032, United States
Investigational Site 023
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Norfolk, Virginia, 23507, United States
Investigational Site 024
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Madrid, 28850, Spain
Investigational Site 025
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Belgrade, 11000, Serbia
Investigational Site 026
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Belgrade, 11040, Serbia
Investigational Site 027
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Ottawa, Ontario, K1N 6N5, Canada
Investigational Site 028
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Montpellier, 34090, France
Investigational Site 029
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Genoa, 16132, Italy
Investigational Site 030
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Los Angeles, California, 90048, United States
Investigational Site 031
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Warsaw, 02-507, Poland
Investigational Site 032
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Voula, 166 73, Greece
Investigational Site 033
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Udine, 33100, Italy
Investigational Site 034
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Athens, 115 28, Greece
Investigational Site 035
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London, SE1 7EH, United Kingdom
Investigational Site 036
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Pessac, 33600, France
Investigational Site 037
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Toulouse, 31400, France
Investigational Site 038
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Toulouse, 31400, France
Investigational Site 039
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Nea Ionia, 142 33, Greece
Investigational Site 040
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Genoa, 16147, Italy
Investigational Site 041
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Varese, 21100, Italy
Investigational Site 042
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Burlington, Vermont, 05401, United States
Investigational Site 043
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Baltimore, Maryland, 21287, United States
Investigational Site 044
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Santa Monica, California, 90404, United States
Investigational Site 045
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Richmond, Virginia, 23284, United States
Investigational Site 046
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Kansas City, Missouri, 66160, United States
Investigational Site 047
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London, NW3 2QG, United Kingdom
Investigational Site 048
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Barcelona, 08017, Spain
Investigational Site 050
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Kansas City, Missouri, 64111, United States
Investigational Site 050
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Padua, 35143, Italy
Investigational Site 051
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Warsaw, 02-097, Poland
Investigational Site 052
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Dresden, 01069, Germany
Investigational Site 053
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Phoenix, Arizona, 85054, United States
Investigational Site 054
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Boston, Massachusetts, 02411, United States
Investigational Site 055
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Minneapolis, Minnesota, 55407, United States
Investigational Site 056
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Milan, 20132, Italy

Conditions

Explore the condition pages connected to this study.

PERICARDITIS PERICARDITIS PERICARDITIS ACUTE PERICARDITIS ACUTE RECURRENT PERICARDITIS