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New hope for heart inflammation sufferers: KPL-387 trial launches

NCT ID NCT07010159

Recruiting now Disease control Sponsor: Kiniksa Pharmaceuticals International, plc Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 28 times

Summary

This study tests whether a new drug called KPL-387 can safely and effectively treat recurrent pericarditis, a condition where the lining around the heart becomes inflamed again and again. About 165 adults who still have symptoms despite standard treatments will take part. The goal is to see if KPL-387 can reduce flare-ups and pain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Investigational Site 001

    WITHDRAWN

    Columbus, Georgia, 31904, United States

  • Investigational Site 002

    WITHDRAWN

    Overland Park, Kansas, 66221, United States

  • Investigational Site 003

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • Investigational Site 004

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Investigational Site 005

    RECRUITING

    Austin, Texas, 78705, United States

  • Investigational Site 006

    RECRUITING

    Charlottesville, Virginia, 22903, United States

  • Investigational Site 007

    RECRUITING

    Milan, 20157, Italy

  • Investigational Site 008

    RECRUITING

    San Francisco, California, 94158, United States

  • Investigational Site 009

    RECRUITING

    Cincinnati, Ohio, 45219, United States

  • Investigational Site 010

    RECRUITING

    Barcelona, 8035, Spain

  • Investigational Site 011

    RECRUITING

    Murcia, 30120, Spain

  • Investigational Site 012

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Investigational Site 013

    RECRUITING

    Houston, Texas, 77030, United States

  • Investigational Site 014

    RECRUITING

    Indianapolis, Indiana, 46184, United States

  • Investigational Site 015

    RECRUITING

    New York, New York, 10016, United States

  • Investigational Site 016

    RECRUITING

    Westminster, Colorado, 80023, United States

  • Investigational Site 017

    RECRUITING

    Southampton, SO17 1BJ, United Kingdom

  • Investigational Site 018

    RECRUITING

    Gilbert, Arizona, 85297, United States

  • Investigational Site 019

    RECRUITING

    Poitiers, 86000, France

  • Investigational Site 020

    RECRUITING

    London, EC1A 7BE, United Kingdom

  • Investigational Site 021

    RECRUITING

    Paris, 75013, France

  • Investigational Site 022

    RECRUITING

    New York, New York, 10032, United States

  • Investigational Site 023

    RECRUITING

    Norfolk, Virginia, 23507, United States

  • Investigational Site 024

    RECRUITING

    Madrid, 28850, Spain

  • Investigational Site 025

    RECRUITING

    Belgrade, 11000, Serbia

  • Investigational Site 026

    RECRUITING

    Belgrade, 11040, Serbia

  • Investigational Site 027

    RECRUITING

    Ottawa, Ontario, K1N 6N5, Canada

  • Investigational Site 028

    RECRUITING

    Montpellier, 34090, France

  • Investigational Site 029

    RECRUITING

    Genoa, 16132, Italy

  • Investigational Site 030

    RECRUITING

    Los Angeles, California, 90048, United States

  • Investigational Site 031

    RECRUITING

    Warsaw, 02-507, Poland

  • Investigational Site 032

    RECRUITING

    Voula, 166 73, Greece

  • Investigational Site 033

    RECRUITING

    Udine, 33100, Italy

  • Investigational Site 034

    RECRUITING

    Athens, 115 28, Greece

  • Investigational Site 035

    RECRUITING

    London, SE1 7EH, United Kingdom

  • Investigational Site 036

    RECRUITING

    Pessac, 33600, France

  • Investigational Site 037

    RECRUITING

    Toulouse, 31400, France

  • Investigational Site 038

    RECRUITING

    Toulouse, 31400, France

  • Investigational Site 039

    RECRUITING

    Nea Ionia, 142 33, Greece

  • Investigational Site 040

    RECRUITING

    Genoa, 16147, Italy

  • Investigational Site 041

    RECRUITING

    Varese, 21100, Italy

  • Investigational Site 042

    RECRUITING

    Burlington, Vermont, 05401, United States

  • Investigational Site 043

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • Investigational Site 044

    RECRUITING

    Santa Monica, California, 90404, United States

  • Investigational Site 045

    RECRUITING

    Richmond, Virginia, 23284, United States

  • Investigational Site 046

    RECRUITING

    Kansas City, Missouri, 66160, United States

  • Investigational Site 047

    RECRUITING

    London, NW3 2QG, United Kingdom

  • Investigational Site 048

    RECRUITING

    Barcelona, 08017, Spain

  • Investigational Site 050

    RECRUITING

    Kansas City, Missouri, 64111, United States

  • Investigational Site 051

    RECRUITING

    Padua, 35143, Italy

  • Investigational Site 051

    RECRUITING

    Warsaw, 02-097, Poland

  • Investigational Site 052

    RECRUITING

    Dresden, 01069, Germany

Conditions

Explore the condition pages connected to this study.

PERICARDITIS PERICARDITIS PERICARDITIS ACUTE PERICARDITIS ACUTE RECURRENT PERICARDITIS