PCOS

This early-stage trial tests whether bicalutamide, a drug that blocks male hormones, can reduce liver fat and stiffness in women with PCOS and nonalcoholic fatty liver disease (NAFLD). About 50 women aged 18-42 will receive either the drug or a placebo for a short time. The goal …

This study looks at whether taking fish oil supplements along with the standard drug metformin can help protect the heart in women with Polycystic Ovary Syndrome (PCOS). PCOS often leads to high testosterone, which can cause blood sugar and cholesterol problems, raising the risk …

This study tests whether adding cabergoline to letrozole helps women with PCOS ovulate more often than letrozole alone. About 72 women aged 18-35 will take either the combo or letrozole only for up to 3 menstrual cycles. Doctors will track ovulation using home tests, blood tests,…

This study looks at whether women with PCOS have early signs of heart and blood vessel problems, and how different treatments might affect those signs. About 120 women will have their heart function tested before and after a sugar drink, and again after 6 months of treatment. The…

This study looks at how androgens (a type of sex hormone) might influence fatty liver disease in young women. Researchers will compare women with and without PCOS, a condition linked to high androgen levels and liver fat. The goal is to understand how liver health changes over ti…

This study looks at three hormones made by fat tissue (leptin, resistin, and omentin-1) in women with PCOS, with or without insulin resistance, compared to women without PCOS. Researchers want to see if these hormones are linked to metabolic problems. About 300 women aged 18-45 w…

This study compares two ways to screen embryos in women with polycystic ovary syndrome (PCOS) who are doing IVF. One method looks at DNA methylation patterns (PIMS), the other looks at chromosome health (PGT-A). The goal is to see if PIMS can lower the chance of early pregnancy l…