PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8
Clinical trials for PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8 explained in plain language.
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Experimental cocktail aims to reboot immune attack on tough cancers
Disease control TerminatedThis early-phase study tested a drug called plinabulin combined with radiation and immunotherapy in 19 people with advanced cancers (like lung, bladder, or melanoma) that had stopped responding to standard immunotherapy. The goal was to see if the combination was safe and could s…
Matched conditions: PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 03:12 UTC
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Modified virus targets Hard-to-Treat melanoma in early trial
Disease control TerminatedThis early-phase trial tested a specially modified virus (VSV-IFNb-TYRP1) in 12 people with advanced melanoma that had spread or couldn't be removed. The virus was injected directly into tumors and into a vein to see if it could safely trigger the immune system to attack cancer c…
Matched conditions: PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 26, 2026 02:48 UTC
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Melanoma drug combo trial halted after just 3 patients
Disease control TerminatedThis study tested two drugs, encorafenib and binimetinib, given before surgery to people with a certain type of advanced melanoma (stage IIIB-D) that had spread to lymph nodes. The goal was to see if the drugs could shrink or eliminate the cancer before removal. The trial was sto…
Matched conditions: PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 20, 2026 11:53 UTC
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Melanoma study halted early: could a malaria drug help cancer treatment?
Disease control TerminatedThis study looked at adding hydroxychloroquine (a malaria drug) to standard targeted therapy (dabrafenib and trametinib) for people with advanced BRAF V600E/K melanoma that had high LDH levels. The goal was to see if the combination could delay cancer growth. Only 5 people enroll…
Matched conditions: PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 20, 2026 11:53 UTC