PATHOLOGIC PROCESSES
Clinical trials for PATHOLOGIC PROCESSES explained in plain language.
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Smart oxygen system keeps patients safer, study finds
Disease control CompletedThis study tested a smart oxygen machine that automatically adjusts oxygen levels for hospitalized patients with serious injuries or illnesses. The goal was to keep oxygen in a safe range (90-96%) for the first 72 hours. 300 adults took part to see if the machine worked better th…
Matched conditions: PATHOLOGIC PROCESSES
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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Stem cells aim to save limbs and prevent repeat amputations
Disease control CompletedThis study tested whether injecting donor stem cells into the leg muscles of people undergoing major leg amputation could prevent wound complications and reduce the need for further amputations. 81 adults aged 40-90 with severe artery disease received stem cell injections above a…
Matched conditions: PATHOLOGIC PROCESSES
Phase: PHASE1 • Sponsor: Indiana University • Aim: Disease control
Last updated May 18, 2026 12:03 UTC
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New drug MRX-2843 tested in patients with advanced cancers
Disease control CompletedThis early-phase study tested a new drug called MRX-2843 in 42 adults with advanced or metastatic solid tumors that had not responded to prior treatments. The main goal was to check the drug's safety and find the best dose. Researchers monitored side effects and how the drug move…
Matched conditions: PATHOLOGIC PROCESSES
Phase: PHASE1 • Sponsor: Meryx, Inc. • Aim: Disease control
Last updated May 18, 2026 12:01 UTC
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New malaria drug put to the test in human trial
Knowledge-focused CompletedThis study tested a new experimental malaria drug called MMV367 in 12 healthy adults. Participants were intentionally infected with a controlled, low-level malaria infection to see how well the drug kills the parasite and how safe it is. The goal was to understand the right dose …
Matched conditions: PATHOLOGIC PROCESSES
Phase: PHASE1 • Sponsor: Medicines for Malaria Venture • Aim: Knowledge-focused
Last updated May 26, 2026 04:32 UTC
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HIV study probes hidden clues to heart disease and death risk
Knowledge-focused CompletedThis study looked at blood markers of inflammation, clotting, and blood vessel function in 310 HIV-infected adults and healthy volunteers. The goal was to better understand how these markers, especially D-dimer, relate to HIV and risks like heart disease and stroke. Participants …
Matched conditions: PATHOLOGIC PROCESSES
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC