PARKINSONS DISEASE (PD)

This early-stage study tests whether a supplement called gamma-glutamylcysteine (GGC) can increase levels of a key antioxidant, glutathione, in the brains of people with early Parkinson's disease. Researchers will measure changes in brain chemistry, motor skills, thinking abiliti…

This large clinical trial is testing several potential treatments at once to see if they can slow the progression of Parkinson's disease. About 1,200 people with Parkinson's will take part, and most visits can be done from home. The goal is to find treatments that help people sta…

This phase 3 study tests a treatment called bemdaneprocel, which involves transplanting dopamine-producing nerve cells into the brains of people with Parkinson's disease. The goal is to reduce daily 'off' time when symptoms worsen and increase 'on' time with good movement control…

This study tests a new way to help people with early-stage Parkinson's disease improve hand function. Instead of just playing a video game on a screen, participants will use real physical objects along with the game. The goal is to see if this 'phygital' approach works better tha…

This study tests whether a non-invasive brain stimulation technique called tDCS can improve motor function and reduce fatigue in people with Parkinson's disease. Researchers will apply mild electrical current to the brain area controlling movement over multiple sessions. The stud…

This study uses advanced brain scans to investigate a newly discovered brain network, called SCAN, in people with Parkinson's disease. Researchers want to see if this network is disrupted in Parkinson's and how it connects to other brain areas. The goal is to find a specific brai…

This study looks at why swallowing problems happen in Parkinson's disease. Researchers will use swallowing tests, brain scans, and blood tests in 100 participants to understand the causes and how the brain tries to adapt. The goal is to find better ways to predict and treat these…

This study looks at a gene called csgA found in gut bacteria of people with Parkinson's disease who also have gut problems. Researchers want to know how common this gene is and how it changes over time. The goal is to learn more about the gut's role in Parkinson's, which could he…

This study tests if a mild electrical pulse on the ear can improve decision-making and problem-solving. Researchers will include healthy adults, people with mild cognitive impairment, and those with Parkinson's disease. The goal is to understand how this stimulation affects brain…