PARAGANGLIOMA

This study tests a daily pill called axitinib in adults with rare adrenal gland tumors (pheochromocytoma or paraganglioma) that have spread or cannot be removed. The main goal is to see how many patients' tumors shrink or disappear. Researchers also track how long the disease sta…

This study looks at how safe a radioactive drug called Lutathera is for teenagers aged 12 to 18 with certain rare tumors of the gut or adrenal glands. The goal is to measure radiation doses to organs and track side effects. Lutathera is not a cure; it aims to control tumor growth…

This study tests two immunotherapy drugs, nivolumab and ipilimumab, in adults with over 50 types of rare cancers. The goal is to see if this drug combination can shrink tumors or stop them from growing. The trial is no longer enrolling new participants, but results will help guid…

This study tests a drug called lanreotide in 10 people with advanced or metastatic paraganglioma or pheochromocytoma, rare tumors that release hormones. The goal is to see if lanreotide can slow tumor growth compared to before treatment. Participants receive injections every 4 we…

This study tests whether a combination of two drugs, talazoparib and temozolomide, can shrink advanced rare cancers or stop them from growing. The trial includes 14 adults with rare solid tumors that have not responded to standard treatments. Talazoparib blocks a protein that hel…

This study is testing a new type of PET/CT scan that uses a special tracer (68Ga-DOTATOC) to find neuroendocrine tumors and other related cancers. The goal is to see if this scan is safer and more sensitive than current imaging methods. About 800 people with known or suspected tu…