OUTPATIENT
Clinical trials for OUTPATIENT explained in plain language.
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Higher antidepressant dose linked to more hospital trips for seniors with kidney issues
Knowledge-focused CompletedThis study looked at whether starting older adults with reduced kidney function on a higher dose (50mg) of the antidepressant sertraline is riskier than starting on a lower dose (25mg). Researchers analyzed health records of nearly 7,000 people aged 66+ in Canada to see if the hi…
Matched conditions: OUTPATIENT
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:43 UTC
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Higher antidepressant dose may put elderly kidney patients at risk
Knowledge-focused CompletedThis study looked at the safety of two different starting doses of the antidepressant citalopram in adults aged 66 and older who have reduced kidney function. Researchers analyzed health records of over 7,000 people to see if starting on a 20mg daily dose led to more hospital vis…
Matched conditions: OUTPATIENT
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Higher antidepressant dose may pose risk for elderly with kidney issues
Knowledge-focused CompletedThis study looked at the safety of two different starting doses of a common antidepressant, escitalopram, in adults over 65 with reduced kidney function. Researchers analyzed health records of over 12,000 people to see if starting on a 10 mg daily dose led to more hospital visits…
Matched conditions: OUTPATIENT
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC