OSA

This study tested whether a single dose of the sleep medication lemborexant could help people with moderate-to-severe sleep apnea who wake up too easily during sleep. Ten adults completed two overnight sleep tests, one with the drug and one with a placebo. The main goal was to se…

This small study tested whether a mandibular advancement device (MAD) — a mouthpiece that moves the jaw forward — can reduce how often people with obstructive sleep apnea wake up to urinate at night. Eleven adults with sleep apnea and at least two nightly bathroom trips took part…

This study tested a combination pill called AD109 against a placebo in 646 adults with obstructive sleep apnea who cannot tolerate CPAP machines. The goal was to see if the pill reduces breathing pauses during sleep. Participants took the medication or placebo for 6 months, and r…

This study tested a combination pill called AD109 (aroxybutynin and atomoxetine) against a placebo in 660 adults with obstructive sleep apnea who cannot or will not use a CPAP machine. The goal was to see if the pill reduces breathing pauses during sleep and improves fatigue. Par…

This study looked at how well the diaphragm (the main breathing muscle) works in people with obstructive sleep apnea. Researchers used ultrasound to measure diaphragm movement in 60 adults. The goal was to see if these measurements relate to how severe the sleep apnea is. This wa…

This study looked at how a mix of home and in-clinic circuit exercises affects muscle loss and fatigue in 72 adults aged 30-85 with COPD, sleep apnea, or lingering COVID-19 symptoms. Participants completed 18 exercise sessions, 12 in person. The goal was to understand the body's …

This study looked at how two drugs, atomoxetine and oxybutynin, affect throat muscles in people with obstructive sleep apnea (OSA). The goal was to understand why the combination works better than either drug alone. 27 adults with OSA took part, and researchers measured muscle ac…

This study looked at whether obstructive sleep apnea (OSA) might help cause Alzheimer's disease. Researchers studied 182 older adults aged 65-85, some with and some without sleep apnea, using brain scans and breathing tests. The goal was to understand how sleep disruptions from a…