OROPHARYNX CANCER
Clinical trials for OROPHARYNX CANCER explained in plain language.
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Tailored radiation aims to tame tough throat cancer with fewer side effects
Disease control OngoingThis study tests a personalized radiation approach for people with advanced HPV-related throat cancer that is at high risk of coming back. About 19 participants will receive radiation boosted to the exact tumor shape using special scans, aiming to keep the cancer under control wh…
Matched conditions: OROPHARYNX CANCER
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated May 26, 2026 05:14 UTC
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Immunotherapy may replace chemo in head and neck cancer treatment
Disease control OngoingThis study compares two treatments for advanced head and neck cancer: the immunotherapy drug pembrolizumab (Keytruda) plus radiation versus standard chemotherapy (cisplatin) plus radiation. About 126 participants with p16-positive cancer will be enrolled. The goal is to see if th…
Matched conditions: OROPHARYNX CANCER
Phase: PHASE2 • Sponsor: Loren Mell, MD • Aim: Disease control
Last updated May 26, 2026 05:10 UTC
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New combo aims to skip radiation for head and neck cancer patients
Disease control OngoingThis study tests a combination of two chemotherapy drugs and an immunotherapy drug given before surgery to people with advanced head and neck cancer that can be removed. The goal is to shrink or kill the cancer enough so that patients may not need radiation after surgery, which c…
Matched conditions: OROPHARYNX CANCER
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated May 26, 2026 05:06 UTC
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Radiation-Immuno combo aims to boost HPV throat cancer response before surgery
Disease control OngoingThis study tests whether giving targeted radiation along with two immunotherapy drugs (evorpacept and pembrolizumab) before standard surgery can improve outcomes for people with early-stage HPV-related throat cancer. About 29 adults with stage I disease that can be surgically rem…
Matched conditions: OROPHARYNX CANCER
Phase: PHASE2 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated May 26, 2026 04:37 UTC
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Robotic surgery vs. radiation: which is better for throat cancer patients' quality of life?
Symptom relief OngoingThis study compares two treatments for early-stage oropharyngeal (throat) cancer: robotic surgery or radiation therapy. The goal is to see which approach leads to better swallowing function and overall quality of life. About 138 patients will be randomly assigned to one of the tw…
Matched conditions: OROPHARYNX CANCER
Phase: NA • Sponsor: Christian von Buchwald • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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New MRI technique aims to spare throat cancer patients from lifelong dry mouth
Symptom relief TerminatedThis study was designed to see if using MRI scans to guide radiation therapy can better protect the salivary ducts and reduce dry mouth in people with oropharynx cancer. Dry mouth is a common and lasting side effect of radiation. The plan was to compare patient-reported dry mouth…
Matched conditions: OROPHARYNX CANCER
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 13, 2026 15:59 UTC
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Blood test may spot throat cancer return faster than scans
Knowledge-focused OngoingThis study looks at whether a simple blood test can find signs of HPV-related oropharynx cancer coming back after treatment. Researchers will compare the blood test results with standard imaging and exams in 200 patients. The goal is to see if the blood test is accurate and could…
Matched conditions: OROPHARYNX CANCER
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated May 22, 2026 13:55 UTC
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Diet and exercise program tested for head and neck cancer survivors
Knowledge-focused OngoingThis study looks at whether a special diet and exercise program is practical for people who have had head and neck cancers like mouth or throat cancer. About 40 adults who are getting radiation treatment will take part. The goal is to see if they can stick with the program and fi…
Matched conditions: OROPHARYNX CANCER
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC