ORAL MUCOSITIS

This study tests whether a telehealth program can help cancer survivors prevent mouth sores, gum disease, and tooth decay, and improve their quality of life. About 100 cancer survivors who finished treatment at least 6 months ago will either get the telehealth program or usual ca…

This study tests whether rinsing with virgin coconut oil can prevent severe mouth sores in children and young adults (ages 7-26) undergoing high-dose chemotherapy before a stem cell transplant. About 60 participants will either receive standard mouth rinses or standard rinses plu…

This study tests a light therapy device placed inside the mouth to prevent severe mouth sores in people receiving a stem cell transplant. The sores are a common and painful side effect of the transplant process. Twenty adults will receive daily light treatments using a device cal…

This study tests a single infusion of amimestrocel, made from human umbilical cord cells, to prevent severe mouth and gut sores in 22 adults receiving a stem cell transplant. Patients get the infusion 1-2 days before transplant, and researchers will monitor for sores, pain, and s…

This study tests a zinc-based spray (Gel X) to prevent painful mouth sores in 130 people receiving radiation for head and neck cancer. Participants will use either the zinc spray or a baking soda rinse. The goal is to see if the spray reduces sores, eases pain, and speeds healing…

This study tests a special gel and mouthwash (XCM-OM118) in 63 head and neck cancer patients getting radiation, with or without chemo. The goal is to see if it lowers the chance of severe mouth sores and improves quality of life. Patients use the product during radiation and late…

This study tests whether ozone gas therapy, alone or with special toothpaste and mouthwash, can reduce painful mouth sores caused by radiation or chemotherapy. About 50 adults with head and neck cancers who have mouth sores will be randomly assigned to ozone therapy or ozone plus…

This study tests whether high-level laser therapy can reduce painful mouth sores (oral mucositis) in children under 18 who are receiving a bone marrow transplant. Fourteen participants will get laser treatment on their sores, and researchers will compare their pain and healing to…

This study tests if a special light treatment, called photobiomodulation, can reduce the severity and frequency of painful mouth sores caused by radiation therapy in oral cancer patients. About 30 adults who have had surgery for oral cancer and are scheduled for radiation will re…