Could a daily 'Lollipop' light stop mouth sores in transplant patients?
NCT ID NCT05335434
First seen Jan 06, 2026 · Last updated Jun 23, 2026 · Updated 26 times
Summary
This study tests a daily light therapy device placed inside the mouth to prevent severe mouth sores in people receiving a stem cell transplant. Twenty adults will use the device for about 2-3 minutes each day from the start of their conditioning chemotherapy through day 20 after transplant. The main goal is to see how many days of severe mouth sores occur, compared to what is normally expected.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
THOR LX2.3 with LED Lollipop (a light-emitting device placed in the mouth)
What this could lead to
If it works, this could offer a simple, non-drug way to prevent painful mouth sores during stem cell transplant recovery.
What could go wrong
This is a very small pilot study with only 20 people, so results may not apply to everyone. The device may not reduce sores more than standard care.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.