ORAL LICHEN PLANUS

This study tests a new, low-cost handheld device that uses light therapy (photodynamic therapy) to treat pre-cancerous and early cancerous mouth lesions. The goal is to see if this treatment can destroy these lesions without needing surgery. The study will enroll 65 adults with h…

This study will see if artificial intelligence (AI) can accurately diagnose and assess the risk of certain mouth lesions that might turn into cancer. Researchers will use photos of the lesions and images of cells collected by gently brushing the mouth, then compare the AI's perfo…

This study looks at whether a deep dental cleaning (called subgingival instrumentation) can improve symptoms and reduce immune cells in the gums of people with oral lichen planus, a chronic inflammatory condition. Thirty adults with gum involvement will receive the cleaning and b…

This study tests if a mouthwash with sodium hyaluronate and Sh-Oligopeptide-85 can reduce pain and sores from oral lichen planus, a chronic inflammatory condition. About 40 adults with painful mouth lesions will use either the test mouthwash or a standard corticosteroid mouthwash…

This study looks at whether people with oral lichen planus (a chronic mouth condition) have a higher risk for heart problems and blood clots. Researchers will measure natural anticoagulant levels and antiphospholipid antibodies in 55 adults over one year. The goal is to understan…

This study will compare 88 people with oral lichen planus (a chronic mouth condition) to 88 healthy people to see if they have more gum disease. Participants will get standard dental exams. The goal is to understand if these two conditions are linked, which could help dentists pr…