Gum cleaning may ease mouth condition, small study hopes
NCT ID NCT07381595
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a deep cleaning of the gums can improve symptoms in people with oral lichen planus, a chronic inflammatory condition affecting the mouth. Thirty participants will receive the cleaning and be monitored for changes in signs, symptoms, and immune cell levels. The goal is to understand how the procedure affects the disease, not to cure it.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * Clinically and histopathologically confirmed cases of OLP. * OLP predominantly involving the gingiva. * Consent obtained. Exclusion criteria: * Cases which does not fulfil either clinical or histopathological criteria. * Unwilling to participate in the study. * Patients with recorded history of factors that might modify immune response (such as patient on corticosteroids or medically compromised patients or suffering from heart diseases). * Cases undergoing treatment of OLP within past 6 months. * Biopsies with inadequate or non-representative samples * Cases histopathologically diagnosed as Lichenoid Dysplasia or Oral Lichenoid Lesions. * Cases diagnosed with autoimmune disorders.
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Post Graduate Institute of Dental Sciences
Rohtak, Haryana, 124001, India
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a glowing light reveal hidden mouth lesions?
- Aloe vera vs. steroid: which tames oral lichen planus?
- Can a common steroid gel quiet oral lichen planus by altering MicroRNAs?
- A pharmacist in the dentist's chair: could a new team approach tame stubborn mouth conditions?
- New oral spray aims to ease sore throat and canker sores without drugs
- Gum disease link in mouth condition under investigation