OPIOID USE DISORDER (OUD)

This study tests whether adding cannabidiol (CBD) to standard medication (methadone or buprenorphine) can help people with opioid use disorder reduce or stop using illegal opioids. Researchers will track 450 adults over 24 weeks using urine tests and blood samples. The goal is to…

This study tests whether a personalized deep brain stimulation (DBS) device can safely reduce cravings and opioid use in people with severe, long-term opioid addiction that hasn't improved with other treatments. Six adults aged 22-75 will undergo brain mapping to identify craving…

This study looks at whether nurses can take a bigger role in starting methadone treatment for people with opioid use disorder. Currently, doctors must renew prescriptions every two weeks, but there often aren't enough doctors. The study will involve 182 adults starting methadone …

This study looks at whether daily text reminders and mindfulness messages can help people taking medication for opioid use disorder stick to their treatment and better manage cravings, pain, and withdrawal. About 60 adults who recently started or restarted methadone or buprenorph…

This study tests a new way to start methadone treatment for people with opioid use disorder who use fentanyl. Researchers want to see if a higher starting dose can be given safely. 24 adults will be monitored closely after receiving either a standard or a higher loading dose of m…

This study looks at how ibogaine, a plant-based compound, affects brain activity and reduces cravings in people with moderate to severe opioid use disorder. Twenty adults who are already scheduled to receive ibogaine treatment at a licensed clinic in Mexico will undergo brain sca…