OPIOID-RELATED DISORDERS

This study tested a 12-month program where nurses provided phone-based support to 805 adults with depression and possible opioid use disorder. Participants were randomly assigned to receive the nurse care program or usual care. The goal was to see if nurse support could improve t…

This study tested whether a once-monthly injection of buprenorphine works as well as daily pills for people with opioid use disorder living in rural areas. About 140 adults participated, receiving either the injection or daily tablets for 14 weeks. The goal was to see if the mont…

This study tested if deep brain stimulation (DBS) is safe and feasible for people with severe opioid addiction that hasn't improved with other treatments. One participant received either active or sham stimulation to brain areas linked to reward. The goal was to see if DBS could …

This study tested a new program called PRE-FAIR to prevent opioid and methamphetamine addiction in young parents (ages 16-30) who are involved with Oregon's child welfare system. The program combined mental health support, parenting help, and drug use monitoring. 241 parents were…

This study tested a simple checklist for hospital staff to help people who inject drugs get HIV prevention medicine (PrEP) and addiction treatment. Researchers worked with 60 HIV-negative adults with opioid use disorder at a hospital in Alabama. The goal was to see if this approa…

This study looked at how cannabidiol (CBD) affects the brain in people with opioid use disorder who are stable on methadone. Researchers gave 66 participants either CBD or a placebo and used brain scans to measure changes in brain activity related to craving and anxiety. The goal…

This study looked at 80 women having breast reduction surgery to see which nerve block—erector spinae plane block or serratus anterior plane block—works better for pain after surgery. The goal was to reduce pain and the need for strong painkillers like opioids. Researchers measur…

This study tested a small nerve-stimulating device called the Bridge to see if it can reduce opioid withdrawal symptoms. 46 adults with opioid use disorder stayed in a research unit for 2-3 weeks. Some used the active device, some used a sham device, and some took a standard with…

This small study tested whether people with chronic pain and opioid problems would actually do art on their own at home, and if it helped their pain and mood. Thirty-one adults completed surveys before and after up to four art sessions. The results suggest that self-guided artmak…

This study tested a program called TOPPS for people taking buprenorphine for opioid use disorder who also have chronic pain. The program uses counseling and education to help patients manage pain without turning to opioids. Researchers compared it to a health education group in 1…

This study followed 71 babies born to mothers being treated for opioid use disorder during pregnancy. Researchers compared two forms of buprenorphine (a monthly shot vs. daily under-the-tongue tablets) to see if one led to better infant brain development. The goal was to gather i…

This study tested a mobile app called App for Independence-O (A4i-O) designed to support people with opioid use disorder. Fourteen adults used the app for one month while in outpatient treatment. The goal was to see if the app works well and is easy to use, not to measure health …

This study looked at pregnant women being treated for opioid use disorder to understand how two forms of buprenorphine (a once-monthly shot vs daily pills) affect mothers and their newborns. Researchers measured drug levels in the blood, fetal heart rate, and baby health after bi…