OPEN-ANGLE GLAUCOMA

This early-stage study tested a tiny implant placed inside the eye that slowly releases medication to lower eye pressure in people with mild-to-moderate open-angle glaucoma. The goal was to find a dose that works well with few side effects. 37 adults participated, and the implant…

This study tested a new eye drop called NCX 470 in 696 people with open-angle glaucoma or high eye pressure. Participants used the drop once daily for up to 12 months, and researchers measured how well it lowered eye pressure compared to a standard treatment, latanoprost. The goa…

This study tested whether aiming a laser at the nasal or inferior part of the eye works better to lower pressure in people with open-angle glaucoma. Thirteen adults with high eye pressure received the laser treatment, and researchers measured how much their eye pressure dropped. …

This study tested a gel stent implant placed outside the eye to lower pressure in people with open-angle glaucoma. 74 adults aged 45 and older took part and were followed for 12 months. The goal was to see if the stent safely reduces eye pressure by at least 20% with the same or …

This study tested a small device called the Hydrus Microstent in 217 adults with open-angle glaucoma that was not well controlled with standard treatments. The goal was to see if the implant could safely lower eye pressure and reduce the need for eye drops. Results showed that ma…

This study tested a new eye drop called Reformulated PG324 to see how safe and effective it is at lowering eye pressure in people with open-angle glaucoma or ocular hypertension. About 489 participants took part in this phase 3 trial. The main goal was to measure eye pressure at …

This study tested two new eye drops (AR-17043 and a combination with latanoprost) to see if they safely lower eye pressure in people with open-angle glaucoma or high eye pressure. A total of 426 adults took part. The goal was to find the best dose for reducing pressure, which is …

This study looked at how NCX 470 eye drops affect the fluid dynamics inside the eye. 18 healthy volunteers or people with high eye pressure received either the active drop or a placebo for 8 days. Researchers measured fluid production, drainage, and pressure to understand how the…