NON-CYSTIC FIBROSIS BRONCHIECTASIS

This study tests an inhaled drug called CSL787 in adults with non-cystic fibrosis bronchiectasis, a lung condition that causes chronic cough and infections. The goal is to see if the drug can delay or prevent sudden worsening of symptoms (flare-ups) compared to a placebo. About 4…

This study tests whether a new drug, SAR445399, can reduce mucus plugs in the lungs of adults with non-cystic fibrosis bronchiectasis. About 70 participants will receive either the drug or a placebo, and researchers will measure changes in mucus plug scores using CT scans over 24…

This study tests an inhaled drug called ensifentrine in people with non-cystic fibrosis bronchiectasis, a lung condition that causes frequent infections and breathing problems. About 284 adults will receive either the drug or a placebo twice daily for at least 24 weeks. The main …

This study tests whether a device called SIMEOX, which uses gentle air pulses to help clear mucus from the lungs, can improve quality of life and reduce serious lung infections in people with non-cystic fibrosis bronchiectasis. Participants will use the device at home along with …

This study tests an inhaled drug called GDC-6988 in people with lung conditions that cause thick mucus, such as COPD and non-cystic fibrosis bronchiectasis. The main goals are to check the drug's safety and how well it works. About 128 adults with stable disease will take part.

This study tests whether a breathing and respiratory muscle training program done at home, with support from a health coach, can help people with non-cystic fibrosis bronchiectasis exercise more and improve lung function. About 50 adults with this chronic lung condition will part…

This study looks at a chronic lung condition called non-cystic fibrosis bronchiectasis, where airways are damaged and cause coughing and infections. Researchers will study 320 patients and healthy volunteers in China to find biological markers and disease patterns. The goal is to…

This study is observing 750 adults with non-cystic fibrosis bronchiectasis to develop a model that can identify different types of the disease based on patient data. The goal is to help doctors predict how the disease will progress and tailor care more effectively. No new treatme…

This early-stage study tests the safety of a new drug called RSS0343 in 48 healthy adults aged 18 to 55. Participants take the drug or a placebo by mouth, and researchers monitor side effects and how the drug moves through the body. The goal is to gather safety and dosing informa…